正念减压疗法和正念认知疗法安全性的meta分析  

A meta-analysis of safety of mindfulness-based s stress.reduction therapy and mindfulness-based cognitive therapy

作　　者：谢静静 李丽霞 柳学华[2] 岳伟华[2] XIE Jingjing;LI Lixia;LIU Xuehua;YUE Weihua(SchooI of Nursing,Peking University,Beijing 100191,China;Peking University Sixth Hospita1,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National CIinical Rese arch Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100083,China)

机构地区：[1]北京大学护理学院,北京100091 [2]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100083

出　　处：《中国心理卫生杂志》2024年第1期73-83,共11页Chinese Mental Health Journal

摘　　要：目的:探讨正念减压疗法(MBSR)和正念认知疗法(MBCT)相关不良事件及影响因素。方法:检索PubMed、CINAHL、Embase、WebofScience、Scopus、Proquest、ScienceDirect、PsycINFO数据库及未发表的研究报告和灰色文献中有关MBSR和MBCT不良事件或不良反应的随机对照试验,并追溯纳入文献的参考文献和相关期刊,检索时限截止到2022年6月1日。采用RevMan5.4软件进行meta分析,计算合并OR(95%CI)值。结果:共纳入15篇文献,包含2841名研究对象。Meta分析结果显示,MBSR或MBCT干预组和对照组发生不良事件或不良反应的差异有统计学意义(0R=2.48,95%CI=1.09~1.61;P<0.05);使用的正念干预方法(单独使用MBSR,OR=9.04,95%CI=5.34~15.30)、参与者合并基础疾病(合并精神疾病,OR=1.49,95%CI=1.12~1.97;合并躯体疾病,OR=8.65,95%CI=5.17~14.45)、练习强度(每次>2h,OR=1.43,95%CI=1.04~1.96)及正念师资水平(未经过规范培训,OR=1.96,95%CI=1.20~3.23)是影响MBSR和MBCT治疗过程中可能会出现相关不良事件或不良反应的因素。结论:正念减压治疗或正念认知治疗过程中可能会出现不良事件或不良反应。Objective:To systematically review the adverse events and relatedfactors ofmindfulness-based stress reduction therapy(MBSR)and mindfulness-based cognitive therapy(MBCT).Methods:By searching the randomized controlled trails of adverse events and adverse effects of MBSR and MBCT from PubMed,CINAHL,Embase,Web of Science,Scopus,Proquest,ScienceDirect,PsycINFO databases and unpublished studies and grey literature,and traces the references and related journals of the included studies.The databases were searched from inception to June 1,2022.Meta analysis was performed byusing RevMan 5.4 softwareto calculate combined odds radio(OR)and 95%CI.Results:Fifteen literatures with a total of 2841subjects were included in the study.The results of meta-analysis showed that there were statistically significant differences in the incidence of adverse events www.cmhj.cn or adverse reactions between theMBSR and MBCT group and the control group(0R=2.48,95%CI:1.09-1.61,P<0.05).The mindfulness-based intervention methods(only MBSR,OR=9.04,95%CI:5.34-15.30),the un-derlying diseases of the participants(complicated with mental disorders,OR=1.49,95%CI:1.12-1.97;compli-cated with physical diseases,OR=8.65,95%CI:5.17-14.45),exercise intensity(once a week for 8 weeks,each time more than 2 hours,OR=1.43,95%CI:1.04-1.96)and the level of mindfulness therapists(did not underg-one standardized training,OR=1.96,95%CI:1.20-3.23)were factors that may affect the occurrence of adverse events or adverse reactions in the process of MBSR and MBCT.Conclusion:During the MBSR and MBCT thera-py,there may be occur adverse events or adverse effects.

关 键 词：正念减压疗法 正念认知疗法 不良事件 不良体验 不良反应 安全性 随机对照试验 META分析 

分 类 号：R749.055[医药卫生—神经病学与精神病学]