22例鼻咽癌合并急性脑梗死临床特点分析  

The Analysis Of Clinical Characteristics Of Nasopharyngeal Carcinoma Complicated With Acute Cerebral Infarction

作　　者：何芷怡 车秀娟 张广智[2] HE Zhi-yi;CHE Xiu-juan;ZHANG Guang-zhi(Department of Neurological Intensive Care Unit,2.Department of Neurology,Maoming People's Hospital,Maoming,525000)

机构地区：[1]广东省茂名市人民医院神经重症医学科,525000 [2]广东省茂名市人民医院神经内一科,525000

出　　处：《岭南急诊医学杂志》2023年第6期546-549,共4页Lingnan Journal of Emergency Medicine

摘　　要：目的:总结鼻咽癌合并急性脑梗死患者的临床特点,探讨发病机制及治疗方案。方法:本研究共入组22例鼻咽癌合并急性脑梗死患者,分析患者临床流行病学及影像学特点,并初步探讨血管内治疗方案的安全性及有效性。结果:在22例患者中,7例(31.8%)为鼻咽未分化型非角化性癌;12例(54.5%)无脑血管疾病高危因素;3例(13.6%)有两项高危因素。所有患者接受颅脑MRI检查排除肿瘤转移。发现年龄、高血压、糖尿病、吸烟等为急性脑梗死独立危险因素(P<0.05)。结论:放疗诱发的颈动脉损伤可导致急性脑梗死;且在无传统脑血管危险因素患者中易被忽略。临床上可通过颈动脉彩超等方法动态监测,积极预防,及时干预。Objective:To summarize the clinical characteristics,pathogenesis,and treatment of nasopharyngeal carcinoma with acute cerebral infarction.Method:This retrospective study involved 22 cases of nasopharyngeal carcino-ma with acute cerebral infarction.We analyzed clinical epidemiology,imaging features,and preliminarily assessed the safety and efficacy of endovascular treatment.Results:Among the 22 patients,7(31.8%)had undifferentiated non-kera-tinizing nasopharyngeal carcinoma;12(54.5%)had no high-risk factors for cerebrovascular disease;3(13.6%)had two high-risk factors.All underwent brain MRI to rule out tumor metastasis.Age,hypertension,diabetes,and smoking were identified as independent risk factors for acute cerebral infarction(P<0.05).Conclusion:Radiotherapy can cause carotid damage leading to acute cerebral infarction,especially in patients without traditional cerebrovascular risks.Clini-cally,using carotid ultrasound for monitoring and early intervention is crucial.

关 键 词：急性脑梗死 鼻咽癌 临床特点 血管内治疗 支架植入术 

分 类 号：R739.63[医药卫生—肿瘤] R743.3[医药卫生—临床医学]