Automated evaluation of parapapillary choroidal microvasculature in crowded optic discs:a controlled,optical coherence tomography angiography study  

作　　者：Hatice Arda Hidayet Sener Ozge Temizyurek Hatice Kubra Sonmez Duygu Gulmez Sevim Cem Evereklioglu Fatih Horozoglu Ayse Busra Gunay Sener 

机构地区：[1]Department of Ophthalmology,Erciyes University Medical Faculty,Kayseri 38090,Turkey [2]Department of Medical Informatics and Biostatistics,Erciyes University Medical Faculty,Kayseri 38090,Turkey

出　　处：《International Journal of Ophthalmology(English edition)》2024年第1期113-118,共6页国际眼科杂志（英文版）

摘　　要：AIM:To compare superficial and deep vascular properties of optic discs between crowded discs and controls using optical coherence tomography angiography(OCT-A).METHODS:Thirty patients with crowded discs,and 47 control subjects were enrolled in the study.One eye of each individual was included and OCT-A scans of optic discs were obtained in a 4.5×4.5 mm^(2) rectangular area.Radial peripapillary capillary(RPC)density,peripapillary retinal nerve fiber layer(pRNFL)thickness,cup volume,rim area,disc area,cup-to-disc(c/d)area ratio,and vertical c/d ratio were obtained automatically using device software.Automated parapapillary choroidal microvasculature(PPCMv)density was calculated using MATLAB software.When the vertical c/d ratio of the optic disc was absent or small cup,it was considered as a crowded disc.RESULTS:The mean signal strength index of OCT-A images was similar between the crowded discs and control eyes(P=0.740).There was no difference in pRNFL between the two groups(P=0.102).There were no differences in RPC density in whole image(P=0.826)and peripapillary region(P=0.923),but inside disc RPC density was higher in crowded optic discs(P=0.003).The PPCMv density in the inner-hemisuperior region was also lower in crowded discs(P=0.026).The pRNFL thickness was positively correlated with peripapillary RPC density(r=0.498,P<0.001).The inside disc RPC density was negatively correlated with c/d area ratio(r=-0.341,P=0.002).CONCLUSION:The higher inside disc RPC density and lower inner-hemisuperior PPCMv density are found in eyes with crowded optic discs.

关 键 词：crowded optic disc ischemic optic neuropathy optical coherence tomography angiography parapapillary choroidal microvasculature 

分 类 号：R749.16[医药卫生—神经病学与精神病学]