以心源性栓塞和Löffler心内膜炎为特征的嗜酸性粒细胞白血病一例  

Eosinophilic leukemia with cardiogenic embolism and Löffler endocarditis as the characteristics:a case report

作　　者：杨婷 曾晓霞 陈雪[2] 罗瑞卿[2] 丁卫江[2] 漆学良[2] Yang Ting;Zeng Xiaoxia;Chen Xue;Luo Ruiqing;Ding Weijiang;Qi Xueliang(Department of Neurology,Yanshan County People′s Hospital,Shangrao,Jiangxi 334500,China)

机构地区：[1]江西省上饶市铅山县人民医院神经内科,334500 [2]南昌大学第二附属医院神经内科

出　　处：《中国脑血管病杂志》2023年第12期846-849,共4页Chinese Journal of Cerebrovascular Diseases

摘　　要：嗜酸性粒细胞白血病合并心源性栓塞、L ffler心内膜炎为主要表现的病例较罕见,早期正确诊断和及时治疗可改善预后。当患者存在神经功能缺损症状且伴嗜酸性粒细胞增高,应积极寻找脑梗死少见病因型,必要时完善骨髓涂片检查、白血病相关融合基因检测及对L ffler心内膜炎及心室内血栓的排查。该例以心源性栓塞、L ffler心内膜炎为主要表现的嗜酸性粒细胞白血病患者,经积极治疗原发病,症状改善,嗜酸性粒细胞降至正常。本研究总结患者病例资料,并结合文献复习,希望提高临床医师对该罕见病的认识。The occurrence of eosinophilic leukemia complicated with cardiogenic embolism and L ffler endocarditis are relatively rare.Early accurate diagnosis and prompt treatment can improve the its prognosis.When patients have symptoms of neurological impairment accompanied by increased eosinophils,the rare etiological type of cerebral infarction should be actively screened.Further improvements are needed in the examination of bone marrow smears,detection of fusion genes associated with leukemia,screening for L ffler endocarditis,and identification of intraventricular thrombi.In this case,the main manifestations of eosinophilic leukemia were cardiogenic embolism and L ffler endocarditis.After active treatment,the symptoms improved,and the eosinophil count returned to normal.This study summarizes the case data of this patient and combines it with a literature review,with the hope of raising clinicians′understanding of this rare disease.

关 键 词：栓塞性卒中 嗜酸细胞增多综合征 白血病 嗜酸粒细胞 急性 

分 类 号：R733.7[医药卫生—肿瘤]