红须腹菌酸多糖及其羧甲基酸多糖对免疫抑制型小鼠脏器抗氧化作用的影响  

Effect of Acid Refined Polysaccharide from Rhizopogon Rubescens and Carboxymethylation of RPRR-S on the Antioxidant Effect of Immunosuppressed Mice Organs

作　　者：袁梦晗 张夜路 丁慧敏 黄馨阅 陶明煊[1] Yuan Menghan;Zhang Yelu;Ding Huimin;Huang Xinyue;Tao Mingxuan(School of Food Science and Pharmaceutical Engineering,Nanjing Normal University,Nanjing 210023,China)

机构地区：[1]南京师范大学食品与制药工程学院,江苏南京210023

出　　处：《南京师范大学学报（工程技术版）》2023年第4期57-66,共10页Journal of Nanjing Normal University(Engineering and Technology Edition)

基　　金：浙江省动物蛋白食品精深加工技术重点实验室开放基金项目。

摘　　要：以红须腹菌酸多糖(Acid Refined polysaccharide from Rhizopogon rubescens,RPRR-S)及羧甲基红须腹菌酸多糖(Carboxymethylation of RPRR-S,CM-RPRR-S)为试验材料,通过测定小鼠肾脏、心脏和肝脏的丙二醛(malondialdehyde,MDA)、还原型谷胱甘肽(glutathione,GSH)含量以及其过氧化氢酶(catalase,CAT)、超氧化物歧化酶(superoxide dismutase,SOD)和谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)的活性,研究红须腹菌酸多糖及羧甲基红须腹菌酸多糖对免疫抑制型小鼠肾脏、心脏和肝脏抗氧化作用的影响.结果显示:红须腹菌酸多糖及羧甲基红须腹菌酸多糖对免疫抑制型小鼠肾脏、心脏和肝脏均具有显著的抗氧化作用,能在一定程度上保护并恢复机体损伤的器官,其保护作用随着多糖浓度的增加而增强;且在相同质量浓度下,羧甲基红须腹菌酸多糖效果更明显.Acid Refined polysaccharide from Rhizopogon rubescens(RPRR-S)and Carboxymethylation of RPRR-S(CM-RPRR-S)are used as experimental materials,the contents of malondialdehyde(MDA),glutathione(GSH)and the activities of catalase(CAT),superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in mouse kidney,heart and liver are determined to explore the effects of RPRR-S and CM-RPRR-S on the antioxidant effect of kidney,heart and liver of immunosuppressed mice.The results show that RPRR-S and CM-RPRR-S have significant antioxidant effects on the kidneys,hearts and livers of immunosuppressive mice,which can protect and restore damaged organs to a certain extent,and their protective effects increase with the increase of polysaccharide concentration.And under the same mass liquidity,the effect of CM-RPRR-S is more obvious.

关 键 词：红须腹菌酸多糖 羧甲基红须腹菌酸多糖 肾脏 心脏 肝脏 抗氧化 

分 类 号：TS201.4[轻工技术与工程—食品科学]