术前铁蛋白/白蛋白表达对胸段食管癌胸腔镜术后并发胃排空障碍的预测  

Prediction of Preoperative Ferritin/Albumin Expression on Gastric Emptying Disorder After Thoracoscopic Surgery for Thoracic Esophageal Carcinoma

作　　者：吕明闯[1] LU Mingchuang(Department of Thoracic Surgery,Nanyang Second General Hospital,Nanyang 473000,China)

机构地区：[1]南阳市第二人民医院胸外科,河南南阳473000

出　　处：《河南医学研究》2023年第22期4122-4125,共4页Henan Medical Research

摘　　要：目的 分析术前铁蛋白(FERR)/白蛋白(ALB)表达对胸段食管癌胸腔镜术后并发胃排空障碍的预测价值。方法 选取南阳市第二人民医院2020年11月至2022年11月收治的120例接受胸腔镜手术的胸段食管癌患者,术前接受FERR、ALB水平检测,计算FERR/ALB。根据术后14 d内是否发生胃排空障碍将患者分为发生组(10例)和未发生组(110例),比较两组基线资料和术前FERR/ALB表达情况,绘制受试者工作特征(ROC)曲线,分析术前FERR/ALB表达对胸段食管癌胸腔镜术后并发胃排空障碍的预测价值。结果 发生组合并糖尿病占比高于未发生组(P<0.05),两组性别、年龄、体重指数、手术时长、TNM分期、病理分型、吸烟、饮酒、肿瘤家族病史比较,差异无统计学意义(P>0.05)。发生组FERR水平、FERR/ALB高于未发生组,ALB水平低于未发生组,差异有统计学意义(P<0.05)。FERR、ALB、FERR/ALB表达均可预测胸段食管癌胸腔镜术后并发胃排空障碍(AUC>0.70)。结论 FERR、ALB及FERR/ALB表达对胸段食管癌胸腔镜术后并发胃排空障碍具有一定预测价值,FERR/ALB的预测价值最高。Objective To analyze the predictive value of preoperative ferritin(FERR)/albumin(ALB)expression for gastric emptying disorder after thoracoscopic surgery for thoracic esophageal carcinoma.Methods A total of 120 patients with thoracic esophageal cancer who underwent thoracoscopic surgery in Nanyang Second General Hospital from November 2020 to November 2022 were selected.The levels of FER and ALB were detected before operation,and the FERR/ALB was calculated.According to whether gastric emptying disorder occurred within 14 days after operation,the patients were divided into two groups:the occurrence group(10 cases)and the non-occurrence group(110 cases).The baseline data and preoperative expression of FERR/ALB were compared between the two groups.The curve of receiver’s operating characteristics(ROC)was drawn to analyze the predictive value of preoperative FERR/ALB expression on gastric emptying disorder after thoracoscopic surgery for thoracic esophageal carcinoma.Results The proportion of diabetes mellitus in the combined group was higher than that in the non-combined group(P<0.05).There was no statistical difference in sex,age,body mass index,operation duration,TNM staging,pathological classification,smoking,drinking and family history of tumor between the two groups(P>0.05).The level of FERR and FERR/ALB in the occurrence group were higher than those in the non-occurrence group,and the level of ALB was lower than that in the non-occurrence group,with statistical significance(P<0.05).The expression of FERR,ALB and FERR/ALB can predict gastric emptying disorder after thoracoscopic surgery for thoracic esophageal carcinoma(AUC>0.70).Conclusion The expression of FERR,ALB and FERR/ALB has certain predictive value for gastric emptying disorder after thoracoscopic surgery for thoracic esophageal cancer,and FERR/ALB has the highest predictive value.

关 键 词：胸段食管癌 胸腔镜 胃排空障碍 铁蛋白 白蛋白 

分 类 号：R735.1[医药卫生—肿瘤]