常见成人遗传代谢性肝病的流行病学特征  

Epidemiological characteristics of familiar adult inherited metabolic liver disease

作　　者：梁晨 白丽 段钟平[2,3] 郑素军 Liang Chen;Bai Li;Duan Zhongping;Zheng Sujun(First Department of Liver Disease,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China;Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research,Beijing 100069,China;Fourth Department of Liver Disease,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院肝病中心一科,北京100069 [2]肝衰竭与人工肝治疗研究北京市重点实验室,北京100069 [3]首都医科大学附属北京佑安医院肝病中心四科,北京100069

出　　处：《中华肝脏病杂志》2023年第11期1224-1228,共5页Chinese Journal of Hepatology

基　　金：首都卫生发展科研专项重大专项项目(2022-1-2182);北京市医院管理中心重点医学专业发展计划(扬帆计划)(ZYLX202125);北京市卫生健康委员会高层次公共卫生技术人才学科带头人(学科带头人-02-14);北京市科技新星计划交叉合作课题(20230484455);北京市自然科学基金(7202068、7222093)。

摘　　要：遗传代谢性肝病可以在儿童、青少年、成人等多个年龄段发病。随着诊治水平的提高,越来越多幼年发病的患者可以存活至成年期。原来儿童肝病医生面临的一些疾病,也可在成人肝病门诊出现。这对成人肝病医生提出了新的挑战,要求其掌握更多的专业知识。而我国尚缺乏多数遗传代谢性肝病发病率的具体数据。现简述遗传代谢性肝病的研究发展概况,总结我国常见遗传代谢性肝病的流行病学特征。Inherited metabolic liver diseases can occur in multi-age groups such as children,adolescents,adults,and others.With the improvement of diagnosis and treatment levels,more and more patients with childhood-onset diseases are surviving into adulthood.Some diseases originally faced by pediatric hepatologists also appear in adult hepatology clinics.This raises new challenges for adult hepatologists,requiring them to master more professional knowledge.However,specific data on the incidence rate of most inherited metabolic liver diseases is still lacking in our country.This article reviews the research progress of hereditary metabolic liver diseases and summarizes the epidemiological characteristics of familiar hereditary metabolic liver diseases in China.

关 键 词：成人 流行病学 发病率 遗传代谢性肝病 

分 类 号：R575[医药卫生—消化系统] R181.3[医药卫生—内科学]