幽门螺杆菌感染内镜下胃黏膜表现与^(14)C尿素呼吸试验结果的相关性分析  

Correlation Analysis between Endoscopic Gastric Mucosal Manifestations of Helicobacter Pylori infection and^(14)C Urea Breath Test Result

作　　者：蔡雯 赵玲 吴学勇[1] 涂丽 CAI Wen;ZHAO Ling;WU Xueyong(Wanbei Coal and Electric Group General Hospital,Anhui Suzhou 234000,China)

机构地区：[1]皖北煤电集团总医院消化内科,安徽宿州234000

出　　处：《河北医学》2023年第12期2059-2063,共5页Hebei Medicine

基　　金：2021年度宿州市科技计划项目(编号:SZSKJJZC050)。

摘　　要：目的:探究幽门螺杆菌(Hp)感染内镜下胃黏膜表现与^(14)C尿素呼吸试验结果的相关性。方法:以2021年9月至2022年9月102例慢性胃炎患者为研究对象,均给予内镜检查及^(14)C尿素呼吸试验,比较Hp阳性组及Hp阴性组患者的^(14)C-UBT检测值,并分析慢性胃炎患者内镜下表现与^(14)C-UBT检测值的关系;比较不同胃炎类型患者^(14)C-UBT检测值。结果:Hp感染阳性患者^(14)C-UBT检测值高于Hp感染阴性患者(P<0.05)。内镜下有皱襞增生的慢性胃炎患者^(14)C-UBT检测值大于无皱襞增生,有萎缩患者的^(14)C-UBT检测值大于无萎缩患者(P<0.05)。102例慢性胃炎患者中共检出浅表性胃炎40例、糜烂性胃炎9例、萎缩性胃炎53例,糜烂性胃炎、萎缩性胃炎患者的^(14)C-UBT检测值大于浅表性胃炎患者(P<0.05)。结论:慢性胃炎患者^(14)C-UBT检测值与Hp感染及内镜下表现有关,且胃炎类型也与^(14)C-UBT检测值有关。Objective:To explore the correlation between endoscopic gastric mucosal manifestations of Helicobacter pylori infection and^(14)C urea breath test result.Methods:A total of 102 patients with chronic gastritis from September 2021 to September 2022 were selected as the study subjects.Endoscopic examination and^(14)C urea breath test were performed,and^(14)C-UBT detection value was compared between Hp-positive group and Hp-negative group and the relationship between endoscopic manifestations of patients with chronic gastritis and^(14)C-UBT detection value was analyzed.^(14)C-UBT detection value was compared among patients with different types of gastritis.Results:The^(14)C-UBT detection value of patients with positive Hp infection was higher than that of patients with negative Hp infection(P<0.05).The^(14)C-UBT detection value of chronic gastritis patients with endoscopic plicae hyperplasia was greater than that of patients without plicae hyperplasia.The^(14)C-UBT detection value of patients with atrophy was greater than that of patients without atrophy(P<0.05).40 cases of superficial gastritis,9 cases of erosive gastritis and 53 cases of atrophic gastritis were detected among 102 patients with chronic gastritis.The^(14)C-UBT detection value in patients with erosive gastritis or atrophic gastritis was greater than that of patients with superficial gastritis(P<0.05).Conclusion:The^(14)C-UBT detection value of patients with chronic gastritis is correlated with Hp infection and endoscopic manifestations,and the type of gastritis is also related to^(14)C-UBT detection value.

关 键 词：慢性胃炎 幽门螺旋杆菌 内镜表现 ^(14)C尿素呼吸试验 

分 类 号：R573[医药卫生—消化系统]