血吸虫对肿瘤微环境影响的研究进展  

Research progress on the impact of schistosomiasis on tumor microenvironment

作　　者：竺苑婷 龚平[1] ZHU Yuanting;GONG Ping(Department of Pathology,Jingzhou Hospital Affiliated to Yangtze University,Hubei Jingzhou 434020,China)

机构地区：[1]长江大学附属荆州医院病理科,湖北荆州434020

出　　处：《现代肿瘤医学》2024年第2期375-379,共5页Journal of Modern Oncology

基　　金：湖北省荆州市科技局医疗卫生科技计划重点项目(编号:2015-24-24)。

摘　　要：目前,血吸虫的急性感染在大部分地区已基本得到控制,但在部分区域,尤其是长江中下游地区,血吸虫感染后的继发性病变仍持续存在,并对机体造成不利影响。研究表明血吸虫感染与肿瘤的发生有一定的相关性,而肿瘤相关微环境对肿瘤发生、发展具有重要意义,血吸虫感染后,是否通过影响肿瘤相关微环境,从而改变肿瘤进展方向,其机制尚不明确,本文将就此作一综述。The acute infection of schistosomiasis has been basically controlled in various areas,but in some regions,especially in the middle and lower reaches of the Yangtze River,the secondary lesions still exist after schistosomiasis infection,and continue to cause adverse effects on the body.The literature suggested that schistosomiasis infection would increase the risk of neoplasm,and tumor-associated microenvironment will have great significance on the occurrence and development of tumors.Whether schistosomiasis infection can affect tumor microenvironment that change the direction of tumor progression are not clear.This paper will review the mechanism of the effect of schistosomiasis on tumor microenvironment.

关 键 词：恶性肿瘤 肿瘤微环境 血吸虫感染 

分 类 号：R730[医药卫生—肿瘤]