有氧联合抗阻运动干预对前列腺癌晚期化疗患者癌因性疲乏的应用研究  

Application of aerobic combined with resistance exercise intervention on cancer-related fatigue in patients with advanced prostate cancer undergoing chemotherapy

作　　者：李蕾 潘杰 李萍[1] LI Lei;PAN Jie;LI Ping(Department of Urology,Gulou Hospital Affiliated to Nanjing University School of Medicine,Nanjing,Jiangsu 210008,China)

机构地区：[1]南京大学医学院附属鼓楼医院泌尿外科,江苏南京210008

出　　处：《现代医药卫生》2023年第24期4154-4157,4162,共5页Journal of Modern Medicine & Health

基　　金：南京大学医学院附属鼓楼医院护理课题(ZSB1581);南京大学医院管理研究所课题(NDYG2020048)。

摘　　要：目的探讨有氧联合抗阻运动干预对前列腺癌晚期化疗患者癌因性疲乏的影响。方法随机抽取2021年1月至2022年12月在该院接受前列腺癌化疗的患者90例,将其分为对照组和观察组,每组45例,采用双盲法进行研究。对照组行常规护理干预,观察组行有氧联合抗阻运动护理干预。观察比较两组患者癌因性疲乏、睡眠状况及生活质量的变化。结果经干预后,观察组在癌因性疲乏量表总分及各维度评分方面均显著优于对照组,差异均有统计学意义(P<0.05)。而运动干预后,观察组癌症患者生活质量量表和匹兹堡睡眠质量指数量表各维度评分均有所提高,且显著高于对照组,差异均有统计学意义(P<0.05)。结论有氧联合抗阻运动可减轻前列腺癌晚期化疗患者的癌症疲劳症状,在帮助患者以积极的心态面对疾病的同时改善了患者的身心健康,提高了其生活质量。Objective To explore the effect of aerobic combined with resistance exercise intervention on cancer-related fatigue in patients with advanced prostate cancer undergoing chemotherapy.Methods Patients who received chemotherapy for prostate cancer in the hospital from January 2021 to December 2022 were randomly selected and divided into the control group and theobservation group,with 45 cases in each group.The study was conducted by double-blind method.The control group received routine nursing intervention,while the observation group received continuous intervention of aerobic combined with resistance exercise nursing intervention.The changes of cancer-related fatigue,sleep status and quality of life between the two groupswereobserved and compared.Results After the intervention,the observation group was significantly better than the control group in the total score of fatigue and the scores of each dimension,and the differences were statistically significant(P<0.05).However,after the exercise intervention,the scores of the observation group in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire and Pittsburgh Sleep Quality Index Scale all improved,and were significantly higher than those of the control group,with statistical significance(P<0.05).Conclusion Aerobic combined with resistance exercise can alleviate the symptoms of cancer fatigue in patients with advanced prostate cancer undergoing chemotherapy,help patients face the disease with a positive attitude,improve their physical and mental health and improve their quality of life.

关 键 词：有氧联合抗阻运动 晚期前列腺癌 癌因性疲乏 生活质量 睡眠质量 

分 类 号：R737[医药卫生—肿瘤]