天然药物防龋作用的研究进展  

Research progress of the caries-preventive effects of natural medicines

作　　者：范秉鑫(综述) 吴龙(审校)[2,3] FAN Bingxin;WU Long(Xinjiang Medical University Stomatology College,Urumqi,Xinjiang 830054,China;Department of Cariology and Endodontics,the First Affiliated Hospital/Hospital of Stomatology of Xinjiang Medical University,Urumqi,Xinjiang 830054,China;Xinjiang Uygur Autonomous Region Institute of Stomatology,Urumqi,Xinjiang 830011,China)

机构地区：[1]新疆医科大学口腔医学院,新疆乌鲁木齐830054 [2]新疆医科大学第一附属医院/新疆医科大学附属口腔医院牙体牙髓病科,新疆乌鲁木齐830054 [3]新疆维吾尔自治区口腔医学研究所,新疆乌鲁木齐830011

出　　处：《现代医药卫生》2023年第24期4252-4255,4260,共5页Journal of Modern Medicine & Health

基　　金：新疆医科大学大学生创新训练计划项目(S202210760110)。

摘　　要：龋病是人类最常见的口腔疾病之一,药物防龋是龋病防治的重要手段。近年来,利用天然药物防龋的研究受到国内外学者的广泛关注,并取得很大进展。多种天然药物能够抑制主要致龋菌的生长及其产酸、产糖、黏附能力,抑制生物膜形成或清除已形成生物膜,抑制牙釉质脱矿并促进釉质再矿化。但有关天然药物毒性、天然药物对混合生物膜的作用、天然药物之间的协同作用及天然药物防龋与其他防龋方式的联合还有待进一步研究。该文从天然药物对致龋菌和对牙釉质的作用两方面进行阐述。Dental caries is one of the most common oral diseases in humans,and drug prevention is an important means of caries prevention and treatment.In recent years,the research on using natural medicinesto prevent caries has received extensive attention from domestic and foreign scholars,and great progress has been made.A variety of natural drugs can inhibit the growth of main cariogenic bacteria and their abilities of acid production,sugar production and adhesion,inhibit the formation of biofilms or removal of formed biofilm,inhibit enamel demineralization and promote enamel remineralization.However,about the toxicity of natural medicines,the effect of natural medicineson mixed biofilm,the synergistic effect between natural drugs and the combination of natural medicinesand other caries prevention methods need further study.This article reviewed the effects of natural drugs on cariogenic bacteria and dental enamel.

关 键 词：天然药物 龋病 龋病预防 

分 类 号：R781[医药卫生—口腔医学]