危害分析与关键控制点理论在静脉用药调配中心输液调控管理中的应用效果  

Hazard Analysis and Critical Control Point Theory in Static Distribution Center Practical application of infusion regulation and management

作　　者：高颖 魏斌 侯杰[2] GAO Ying;WEI Bin;HOU Jie(Shandong Public Health Clinical Center,Jinan,Shandong 250013,China;Department of ICU,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan,Shandong 250013,China)

机构地区：[1]山东省公共卫生临床中心,山东济南250013 [2]山东中医药大学附属医院重症监护室,山东济南250013

出　　处：《医药前沿》2023年第34期8-13,共6页Journal of Frontiers of Medicine

基　　金：山东省医药卫生科技发展计划项目(202014051510)。

摘　　要：目的:探讨危害分析与关键控制点理论在静脉用药调配中心(PIVAS)输液调控管理中的应用效果。方法:对山东省某三级医院PIVAS2022年配置的药品进行分析,将2022年1—6月施行常规管理的药品作为对照组,2022年7—12月在常规管理的基础上施行危害分析与关键控制点管理的药品作为观察组。比较两组时限药品配置后的平均放置时间、时限药品规定时间内输注率、输液顺序正确率、成品输液不合格率。结果:观察组时限药品配置后的平均放置时间短于对照组,时限药品规定时间内输注率高于对照组,观察组输液顺序正确率高于对照组,观察组成品输液不合格率低于对照组,差异均有统计学意义(P<0.05)。结论:将危害分析与关键控制点理论应用于PIVAS输液调控管理中,有利于提高成品输液药物安全性、时效性、稳定性,降低患者用药风险,保障患者用药安全。Objective To explore the application effect of Hazard Analysis and Critical Control Point(HACCP)theory in the infusion regulation and management of the pharmacy intravenous admixture service(PIVAS).Methods An analysis was conducted on the drugs dispensed by a tertiary hospital's intravenous admixture service in Shandong Province in 2022.Drugs managed conventionally from January to June 2022 were considered as the control group,while drugs managed based on the implementation of the HACCP management approach on top of conventional management from July to December 2022 were considered as the observation group.A comparison was made between the average placement time of drugs,infusion rates within specified time limits,infusion sequence accuracy,and the rate of finished infusion products being non-compliant between the two groups.Results The observation group showed a significantly lower average placement time for time-limited drug configurations compared to the control group.The infusion rate within the specified time limit was higher in the observation group than in the control group.The observation group exhibited higher accuracy in infusion sequence compared to the control group,and the rate of non-compliance of finished infusion products was lower in the observation group compared to the control group.All differences showed statistical significance(P<0.05).Conclusions Applying the principles of Hazard Analysis and Critical Control Points in PIVAS infusion regulation and management contributes to enhancing the safety,timeliness,and stability of finished infusion drugs,reducing patient medication risks,and ensuring patient medication safety.

关 键 词：静脉用药调配中心 危害分析与关键控制点 时限药品 输液顺序 

分 类 号：R543.6[医药卫生—心血管疾病]