防根面龋牙科材料的研究进展  

Research progress on dental materials for preventing root caries

作　　者：熊净迪 程兴群[1] 吴红崑[1] XIONG Jingdi;CHEN Xingqun;WU Hong-kun(State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Geriatric Dentistry,West China Hospital of Stomatology,Sichuan University,Cheng-du 610041,China)

机构地区：[1]口腔疾病防治全国重点实验室国家口腔医学中心国家口腔疾病临床医学研究中心四川大学华西口腔医院老年口腔科,四川成都610041

出　　处：《口腔疾病防治》2024年第1期64-69,共6页Journal of Prevention and Treatment for Stomatological Diseases

基　　金：国家自然科学基金青年基金(82101002);四川省科技厅重点研发项目(2021YFSY0011,2022NSFSC1359);四川大学华西口腔医学院(华西口腔医院)科研经费资助项目(RCDWJS2021⁃16)。

摘　　要：根面龋是老年人口腔常见病和多发病,发病率和未治疗率高,治疗难度大,可迅速进展引起牙髓根尖周病或残冠根,是老年人失牙的重要原因,已成为严重影响老年人生活质量的常见口腔慢性病之一。因此,根面龋早期干预和防治非常重要。传统防根面龋牙科材料如氟化物、氯己定等在临床中广泛应用,但是其具有牙齿着色、再矿化及杀菌效率低下等缺点。近年来,一系列新兴防根面龋牙科材料如无机纳米材料、胶原交联剂等逐步成为研究热点,新兴材料具有促进深部牙体组织再矿化、作用时间延长、黏附力增强等优点。未来防龋材料应根据根面龋的特点及应用人群进行设计,朝着简便化、高效化、低毒性方面发展。本文对目前防根面龋牙科材料的研究及应用进行综述,以期能够为防根面龋牙科材料的研究提供理论基础,对促进根面龋的有效预防,改善老年人的口腔健康状况和生活质量具有重要意义。The high incidence and untreated rate of root caries,a common and frequently occurring oral disease with challenging treatment in elderly individuals,is the main cause of tooth loss among elderly people,as rapid develop⁃ment results in pulpitis and periapical periodontitis or residual crown and root,which has been regarded as one of the common chronic oral diseases seriously affecting the quality of life of elderly people.Thus,early intervention and pre⁃vention are important.Traditional dental materials for preventing root caries have been widely used in clinical practice;however,they have the disadvantages of tooth coloring,remineralization and low sterilization efficiency.A series of new dental materials for preventing root caries have gradually become a research hotspot recently,which have the advantag⁃es of promoting the mineralization of deep dental tissue,prolonging the action time and enhancing adhesion.Future car⁃ies prevention materials should be designed according to the characteristics of root surface caries and the application population and should be developed toward simplicity,high efficiency and low toxicity.This review describes current re⁃search regarding anti⁃caries prevention material application,serving as a theoretical underpinning for the research of root caries prevention materials,which is important for both promotion in the effective prevention of root caries and im⁃provement in the status of oral health and the quality of life among old people.

关 键 词：根面龋 防龋材料 再矿化 口腔保健 人口老龄化 龋病预防 抗菌材料 氟化物 

分 类 号：R78[医药卫生—口腔医学]