肝脏穿刺组织病理诊断肝脏疾病中免疫组化的应用价值观察  

The Application Value of Immunohistochemistry in the Liver Puncture Histopathology for the Diagnosis of Liver Diseases

作　　者：胡皓彬 李艳春[1] 杨洋 HU Haobin;LI Yanchun;YANG Yang(Department of Pathology,Hunan Provincial People's Hospital(the First Affiliated Hospital of Hunan Normal University),Changsha,Hunan Province,410000 China;Department of Hospital Infection,Changsha Maternal and Child Health Care Hospital,Changsha,Hunan Province,410000 China)

机构地区：[1]湖南省人民医院(湖南师范大学附属第一医院)病理科,湖南长沙410000 [2]长沙市妇幼保健院院感科,湖南长沙410000

出　　处：《系统医学》2023年第20期37-39,47,共4页Systems Medicine

摘　　要：目的研究分析免疫组化用于肝脏穿刺组织病理诊断中作用及对疾病诊断效果影响性。方法选取2021年9月—2022年9月湖南省人民医院收治的肝脏肿瘤疾病患者44例为研究对象,均实施肝脏穿刺组织病理检查、免疫组化肝脏穿刺组织病理检查,以临床综合诊断结果作为金标准,对肝脏穿刺组织病理检查、免疫组化肝脏穿刺组织病理检查疾病诊断作用分析。结果两种检查方式的疾病检出率比较,差异有统计学意义(P<0.05),肝脏穿刺组织病理检查、免疫组化肝脏穿刺组织病理检查疾病的检出率与金标准疾病检出率比较,差异有统计学意义(P<0.05),免疫组化肝脏穿刺组织病理检查疾病诊断准确率(90.91%)高于肝脏穿刺组织病理检查疾病的诊断准确率(86.36%),差异有统计学意义(χ^(2)=25.130,P<0.05)。结论肝脏肿瘤疾病检查,采用免疫组化肝脏穿刺组织病理检查方式,具有较高疾病检出率,同时能够对患者所患肝脏肿瘤疾病类型做出准确诊断。Objective To study and analyze the role of immunohistochemistry in liver puncture tissue diagnosis and the effect of disease diagnosis.Methods 44 patients with liver tumor diseases admitted to Hunan Provincial People's Hospital from September 2021 to September 2022 were selected as the research subjects.Liver puncture tissue pathological examination and immunohistochemistry liver puncture tissue pathological examination were conducted,and the clinical comprehensive diagnostic results were used as the gold standard to analyze the diagnostic role of liver puncture tissue pathological examination and immunohistochemistry liver puncture tissue pathological examination in the disease.Results Comparison of the disease detection rates between the two examination methods,and the difference was statistically significant(P<0.05).The detection rates of liver biopsy tissue pathology and immunohistochemistry liver biopsy tissue pathology were compared with the gold standard disease detection rate,and the difference was statistically significant(P<0.05).The diagnostic accuracy of liver puncture pathological examination by immunohistochemistry(90.91%)was higher than that of liver puncture pathological examination(86.36%),and the difference was statistically significant(χ^(2)=25.130,P<0.05).Conclusion Liver tumor disease examination,the use of immunohistochemical liver puncture histopathology examination,has a high disease detection rate,and can accurately diagnose the liver tumor disease types of patients.

关 键 词：肝脏穿刺 组织病理 免疫组化 应用价值 

分 类 号：R735[医药卫生—肿瘤]