神经性厌食和脑源性神经营养因子关系的研究进展  

Research progress on anorexia nervosa and brain-derived neurotrophic factor

作　　者：陈晨[1] 胡嫣然 陈珏[1] Chen Chen;Hu Yanran;Chen Jue(Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)

机构地区：[1]上海交通大学医学院附属精神卫生中心,200030

出　　处：《神经疾病与精神卫生》2023年第12期879-884,共6页Journal of Neuroscience and Mental Health

基　　金：医工交叉重点项目(YG2022ZD026)。

摘　　要：神经性厌食具有高死亡率、高致残率的特点,其病因和发病机制尚未被完全阐明。广泛存在中枢神经系统的脑源性神经营养因子在神经发育及食欲调节中起重要作用,与神经性厌食的发病相关。本文对神经性厌食与脑源性神经营养因子相关的研究进行了综述,以期为神经性厌食的病因和未来的治疗提供参考。Anorexia nervosa has the characteristics of high mortality and disability rates,and itsetiology and pathogenesis have not been fully elucidated.Brain-derived neurotrophic factors widely presentin the central nervous system play an important role in neural development and appetite regulation,and areassociated with the onset of anorexia nervosa.This article reviews the relationship between anorexia nervosa andbrain-derived neurotrophic factors,aiming to provide reference for the etiology and future treatment of anorexianervosa.

关 键 词：神经性厌食 脑源性神经营养因子 进食障碍 食欲调节 

分 类 号：R749[医药卫生—神经病学与精神病学]