椎基底动脉延长扩张症与脑微出血  

Vertebrobasilar dolichoectasia and cerebral microbleeds

作　　者：吴兆鑫 张道培 Wu Zhaoxin;Zhang Daopei(Henan University of Chinese Medicine,Zhengzhou 450000,China;Department of Encephalopathy(Area 4),the First Affiliated Hospital of Henan University of Chinese MedicineHenan Vertigo Disease Diagnosis and Treatment Center Institute of Vertigo Disease,Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学,郑州450000 [2]河南中医药大学第一附属医院脑病四区,河南省眩晕病诊疗中心,河南中医药大学眩晕病研究所,郑州450000

出　　处：《国际脑血管病杂志》2023年第8期612-617,共6页International Journal of Cerebrovascular Diseases

基　　金：河南省高等学校重点科研项目(22A320036)。

摘　　要：椎基底动脉延长扩张症(vertebrobasilar dolichoectasia,VBD)是以椎基底动脉扩张、延长、迂曲为特征的疾病。脑微出血(cerebral microbleeds,CMBs)是因脑小血管病变引起的以点状微出血为主的脑实质损伤。近年来的研究显示,VBD会增高CMBs的发病率,但二者的关联和病理生理学机制尚不清楚。多种因素均可诱使VBD伴发CMBs。深入认识VBD和CMBs的因果关系及相关机制,有助于此类脑血管病的临床防治。Vertebrobasilar dolichoectasia(VBD)is a disease characterized by the dilation,elongation,and tortuosity of the vertebrobasilar artery.Cerebral microbleeds(CMBs)are brain parenchymal injuries mainly caused by punctate microbleeds due to small vessel lesions.Recent studies have shown that VBD can increase the incidence rate of CMBs,but the correlation and pathophysiological mechanism of the two remain unclear.Multiple factors can induce VBD to accompany CMBs.A deep understanding of the causal relationship and related mechanisms between VBD and CMBs is helpful for the clinical prevention and treatment of such cerebrovascular diseases.

关 键 词：椎底动脉供血不足 基底动脉 脑出血 脑小血管疾病 

分 类 号：R743.34[医药卫生—神经病学与精神病学]