宫颈癌术后患者尿路感染病原菌与易感因素  

Pathogenic bacteria distribution characteristics and susceptibility factors of urinary tract infection in patients with cervical cancer after surgery

作　　者：代小燕 靖芳 王罡 李哲郧 阎蓓 汪晶 DAI Xiao-yan;JING Fang;WANG Gang;LI Zhe-yun;YAN Bei;WANG Jing(Wuhan Third Hospital,Wuhan,Hubei 430064,China;不详)

机构地区：[1]武汉市第三医院妇产科,湖北武汉430064 [2]武汉大学人民医院妇科,湖北武汉430060

出　　处：《中华医院感染学杂志》2023年第23期3640-3643,共4页Chinese Journal of Nosocomiology

基　　金：武汉市卫生计生委医疗卫生科研基金资助项目(WX18D22)。

摘　　要：目的探究宫颈癌术后患者尿路感染的病原菌分布特征与易感因素。方法回顾性选取2019年10月-2022年10月武汉市第三医院收治的200例行宫颈癌手术患者为研究对象,并根据术后是否发生尿路感染分为感染组(43例)及非感染组(157例)。分析宫颈癌术后患者尿路感染现状及病原菌分布特征,通过单因素及多因素分析法分析宫颈癌术后患者尿路感染的易感因素。结果200例宫颈癌术后患者发生尿路感染43例,发生率为21.50%,感染组患者共分离出43株病原菌,其中革兰阴性菌28株(65.12%),革兰阳性菌15株(34.88%)。住院时间长、经尿道留置尿管、术后尿潴留及降钙素原(PCT)水平高为宫颈癌术后患者尿路感染的易感因素(OR=4.121、7.531、6.508、7.561,P<0.05)。结论宫颈癌术后患者尿路感染的发生率较高,且以革兰阴性菌为主;住院时间长、经尿道留置尿管、术后尿潴留及PCT水平高为宫颈癌术后患者尿路感染的易感因素。OBJECTIVE To explore the pathogenic bacterial distribution characteristics and susceptibility factors of urinary tract infection in patients with urinary tract infection after cervical cancer surgery.METHODS A total of 200 patients who underwent cervical cancer surgery in Wuhan Third Hospital from Oct 2019 to Oct 2022 were retrospectively recruited as the research subject.According to whether postoperative urinary tract infection occurred,they were divided into the infection group(43 cases)and the non-infection group(157 cases).The status of urinary tract infection and distribution characteristics of pathogenic bacteria in patients with cervical cancer after surgery were analyzed,and the predisposing factors of urinary tract infection in patients with cervical cancer after surgery was analyzed by univariate and multivariate analysis.RESULTS There were 43 cases of urinary tract infection in 200 patients with cervical cancer after operation,and the incidence was 21.50%.A total of 43 strains of pathogenic bacteria were isolated from patients in the infection group,including 28 strains(65.12%)of gram-negative bacteria and 15 strains(34.88%)of gram-positive bacteria.Long hospital stay,transurethral indwelling catheter,postoperative urinary retention and high levels of procalcitonin(PCT)were the risk factors for urinary tract infection in patients with cervical cancer after surgery(OR=4.121,7.531,6.508,7.561,P<0.05).CONCLUSION The incidence of urinary tract infection in patients after cervical cancer surgery is high,and gram-negative bacteria are the main pathogens.Long hospital stay,transurethral indwelling catheter,postoperative urinary retention and high levels of PCT are susceptibility factors of urinary tract infection in patients after cervical cancer surgery.

关 键 词：宫颈癌 术后 尿路感染 病原菌 易感因素 

分 类 号：R737.3[医药卫生—肿瘤]