综合创新实验:异三聚茚的合成,表征与应用  

Comprehensive Innovative Experiment:Synthesis,Characterization and Application of Isotruxene

作　　者：周岑 洪碧琼 陈毅挺[1] 郑国才[1] 林曦 Zhou Cen;Hong Biqiong;Chen Yiting;Zheng Guocai;Lin Xi(College of Materials and Chemical Engineering,Minjiang University,Fujian,350108)

机构地区：[1]闽江学院材料与化学工程学院,福建350108

出　　处：《当代化工研究》2024年第2期137-140,共4页Modern Chemical Research

基　　金：福建省本科高校教育教学研究项目“对接生物医药材料产业链的产教融合协同育人模式研究”(项目编号:FBJG20220027);闽江学院教改项目及一流课程“基于科研成果转化的有机化学综合性实验项目开发”(项目编号:MJUJG2021B063);闽江学院教改项目及一流课程“氟化工艺特种作业的仿真实训”(项目编号:MJUYLKC2022030);闽江学院教改项目及一流课程“有机化学课程产教融合课堂教学方法改革与实践”(项目编号:MJUCJJG2022009)。

摘　　要：异三聚茚(Isotruxene)是一种新型的稠环芳香化合物,具有成为光电材料的潜力,但受到合成方法的限制,科学界对其研究十分少见。我们发展了一种通过微波反应一步合成异三聚茚的方法,通过柱层析处理得到较纯的异三聚茚,并通过核磁共振谱鉴定了主产物的结构。通过高效液相色谱(HPLC)实现了主产物和副产物的拆分,并测定了主产物的纯度。此外,我们还观测到异三聚茚与硝基化合物混合时的荧光淬灭现象,证实了异三聚茚在爆炸物检测领域的应用潜力。本实验综合了有机合成,仪器分析,物理化学等多个学科的要素,可用于模块化教学,适应不同学时的实验教学要求,既可培养学生的基本操作,又能激发学生的研究兴趣,锻炼学生的综合能力。Isotruxene is a novel polyaromatic compound potentially applicable in organic electronics.However,limited by synthetic methods,the properties of isotruxene and its derivatives remain largely unexplored.In this experiment,we develop a microwave-assisted procedure for one-step synthesis of isotruxene,which yields truxene as a side product.The main product isotruxene is purified by flash chromatography and characterized by NMR,its purity is further determined by HPLC,based on the resolution condition of isotruxene and truxene.The fluorescence quenching phenomenon is observed upon mixing isotruxene and aromatic polynitro compounds,indicating the potential application of isotruxene in the field of explosive detection.The whole experiment involves the synthesis,characterization and application of isotruxene,which integrates the elements of organic synthesis,instrumental analysis,physical chemistry,etc.It can be used for modular teaching adapted to different requirement of teaching hours,not only for basic operations training,but also for stimulating students’research interest and enhancing their comprehensive abilities.

关 键 词：异三聚茚 微波合成 柱层析 高效液相色谱 荧光淬灭 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]