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作 者:HOU Xiaoying LIU Yuchen DU Hongzhi
机构地区:[1]Wuhan Institute of Biomedical Sciences,School of Medicine,Jianghan University,Wuhan 430000,China [2]Cancer Institute,School of Medicine,Jianghan University,Wuhan 430000,China [3]School of Pharmacy,Hubei University of Chinese Medicine,Wuhan 430000,China [4]Center of Traditional Chinese Medicine Modernization for Liver Diseases,Hubei University of Chinese Medicine,Wuhan 430000,China
出 处:《Chinese Journal of Natural Medicines》2023年第12期884-885,共2页中国天然药物(英文版)
基 金:This work was supported by the National Natural Science Foundation of China(No.82204416),the China Postdoctoral Science Foundation(No.2020M670599)and the Scientific Research Project Funding of Jianghan University(No.2023zd055).
摘 要:Emerging epidemiological findings indicate a rising incidence of primary liver cancer,now a foremost contributor to cancer-related mortalities worldwide[1].Several factors play a pivotal role in liver cancer etiology,including infections from the Hepatitis B/C virus,a spectrum of liver diseases like alcoholic and nonalcoholic fatty liver diseases(NAFLD,ASH,and NASH),metabolic aberrations(e.g.,obesity,diabetes),exposure to hepatocarcinogens(e.g.,aflatoxin,aristolochic acid,and iron overload),and disruptions in gut microbiota.Chronic liver diseases,encompassing conditions such as NAFLD and NASH,represent hepatic expressions of metabolic syndrome and bear the potential to culminate in liver cancer.
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