新型载体化妆品安全防腐体系研究  

Research on the Safety and Anti-corrosion System of New Carrier Cosmetics

作　　者：刘沛溢 洪树珠 谢高峰 古颖霖 王峥[3] 王中元 LIU Peiyi;HONG Shuzhu;XIE Gaofeng;GU Yinglin;WANG Zheng;WANG Zhongyuan(Chinese Academy of Inspection and Quarantine,Beijing 100176,China;Zhuhai Guojia New Material Co.,Ltd.,Zhuhai Guangdong 519090,China;College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China)

机构地区：[1]中国检验检疫科学研究院,北京100176 [2]珠海国佳新材股份有限公司,广东珠海519090 [3]北京化工大学生命科学与技术学院,北京100029

出　　处：《北京联合大学学报》2024年第1期57-62,共6页Journal of Beijing Union University

摘　　要：参照《化妆品防腐挑战试验》T/SHRH 017-2019,研究不同成型基质水凝胶防腐体系的防腐效能,结果显示,0.05%乙基己基甘油具有抑菌增效作用。实验分别采用0.05%乙基己基甘油复配0.5%对羟基苯乙酮和0.5%1,2-己二醇,0.05%乙基己基甘油复配0.2%对羟基苯乙酮、0.024%辛酰羟肟酸和0.020%甘油辛酸酯,0.05%乙基己基甘油复配0.1075%对羟基苯乙酮、0.0475%辛酰羟肟酸和0.00125%环庚三烯酚酮作为水凝胶防腐体系,实验结果显示:以上3组防腐体系具有良好的防腐效能。替代防腐成分具有协同抑菌作用,经化妆品防腐挑战试验证明可达到良好的防腐效能,可以更好地满足人们对化妆品安全、温和的需求。By revering to the Cosmetic Preservative Challenge Test T/SHRH 017-2019,a study was conducted on the anti-corrosion efficiency of different anti-corrosion systems in different hydrogel forming substrates.The results showed that 0.05%ethyl glycerol synergistically increased the antibacterial effect.The experiments were conducted using 0.5%p-hydroxyacetophenone and 0.5%1,2-hexadiol,0.2%p-hydroxyacetophenone,0.024%octyl hydroxamic acid and 0.020%glycerol caprylate,0.1075%p-hydroxyacetophenone,0.0475%octanoyl hydroxamic acid,0.00125%cycloheptatrienolone.The experiment results show that the above three anti-corrosion systems have good anti-corrosion performance.The synergistic antibacterial matching of alternative preservative components has been proved to achieve preservative efficacy through cosmetic preservative challenge tests,which can better meet people’s needs for safe and mild cosmetics.

关 键 词：水凝胶 新型载体 化妆品安全 防腐体系 

分 类 号：TQ658[化学工程—精细化工]