超声造影检查对甲状腺良恶性肿瘤的鉴别诊断价值  

Differential diagnosis value of contrast-enhanced ultrasound in benign and malignant thyroid tumors

作　　者：苏小佩 杨瑞静 李俏颖 SU Xiaopei;YANG Rujing;LI Qiaoying(Department of Ultrasonic Diagnosis,the Second Affiliated Hospital of Air Force Medical University,Xi'an 710038,Shaanxi,China)

机构地区：[1]空军军医大学第二附属医院超声诊断科,西安710038

出　　处：《癌症进展》2023年第21期2408-2410,2414,共4页Oncology Progress

摘　　要：目的 探讨超声造影检查对甲状腺良恶性肿瘤的鉴别诊断价值。方法 选取65例甲状腺结节患者,均予以超声弹性成像检查及超声造影检查。病理学检查结果显示良性肿瘤患者40例,恶性肿瘤患者25例。比较两种检查方式对甲状腺良恶性肿瘤的鉴别诊断价值。结果 甲状腺恶性肿瘤患者曲线下面积(AUC)、峰值强度(Peak)、超声弹性成像应变率比值均明显低于良性肿瘤,达峰时间(Tp)明显长于良性肿瘤,差异均有统计学意义(P﹤0.01)。超声造影检查诊断甲状腺恶性肿瘤的灵敏度、特异度、阳性预测值、阴性预测值、准确度、约登指数均高于超声弹性成像检查。结论 超声造影检查较超声弹性成像检查诊断甲状腺良恶性肿瘤的价值更高。Objective To investigate the differential diagnosis value of contrast-enhanced ultrasound in benign and malignant thyroid tumors.Method A total of 65 patients with thyroid nodule were selected and examined by ultrasound elastography and contrast-enhanced ultrasound.Pathological examination results showed that 40 patients had benign tu-mors and 25 patients had malignant tumors.The differential diagnosis value of the two methods in benign and malignant thyroid tumors was compared.Result Patients with malignant thyroid tumors had significantly lower area under the curve(AUC),peak strength(Peak),and elastography strain rate ratios than those with benign tumors,and time to peak(Tp)was significantly longer than that with benign tumors(P<0.01).The diagnostic sensitivity,specificity,positive pre-dictive value,negative predictive value,accuracy and Youden index of contrast-enhanced ultrasound for malignant tumor were higher than those of ultrasound elastography.Conclusion Contrast-enhanced ultrasound is more valuable than ul-trasound elastography in the diagnosis of benign and malignant thyroid tumors.

关 键 词：甲状腺良恶性肿瘤 超声造影 诊断价值 超声弹性成像 

分 类 号：R736.1[医药卫生—肿瘤]