IVIM-DWI及多层螺旋CT与肝细胞肝癌微血管侵犯的相关性分析  

Correlation Analysis of IVIM-DWI and Multilayer Spiral CT with Microvascular Invasion in Hepatocellular Hepatocellular Carcinoma

作　　者：何崇保 庞勇[1] 唐煌 HE Chong-bao;PANG Yong;TANG Huang(Jiangyou Hospital of Traditional Chinese Medicine,Mianyang 621700,Sichuan Province,China)

机构地区：[1]江油市中医医院,四川绵阳621700

出　　处：《中国CT和MRI杂志》2024年第1期103-106,共4页Chinese Journal of CT and MRI

基　　金：2019年绵阳市卫健委课题(201976)。

摘　　要：目的探究体素内不相干运动扩散加权成像(IVIM-DWI)多层螺旋CT(MSCT)与肝细胞肝癌(HCC)微血管侵犯(MVI)的相关性分析。方法选取2019年12月至2022年12月本院收治HCC患者100例临床资料开展回顾性分析。所有患者均经过病理检查、VIM-DWI检查与MSCT检查。100例患者经手术病理确诊为MVI阳性38例,MVI阴性62例。比较两组IVIM-DWI、MSCT定性、定量参数分析的差异,并通过ROC曲线分析IVIM-DWI定量参数、MSCT定量参数及联合数据对HCC存在MVI的诊断价值。结果MVI阳性组边缘毛糙、瘤周低信号、瘤周强化、存在晕征高于MVI阴性组(P<0.05),肿瘤包膜低于MVI阴性组(P<0.05)。两组D、F比较差异无统计学意义(P>0.05),但MVI阳性组ADC、D低于MVI阴性组(P<0.05)。MVI阳性组动脉期CT值低于MVI阴性组(P<0.05),延迟期CT值、门静脉期CT值、肿瘤大小高于MVI阴性组(P<0.05)。ROC曲线分析显示,ADC、D、D、f、延迟期CT值、门静脉期CT值、动脉期CT值、肿瘤大小诊断HCC存在MVI的AUC分别为0.775、0.856、0.609、0.565、0.708、0.728、0.643、0.705。MSCT参数、IVIM-DWI参数、联合数据诊断HCC存在MVI的AUC分别为0.809、0.832、0.920,均具有较好准确性。结论IVIM-DWI、MSCT定性、定量参数均与HCC患者MVI相关,而IVIMDWI、MSCT诊断MVI均具有一定价值,且联合诊断准确性更高。Objective To investigate the correlation analysis between in voxel incoherent motion diffusion-weighted imaging(IVIM-DWI)multilayer spiral CT(MSCT)and microvascular invasion(MVI)in hepatocellular hepatocellular carcinoma(HCC).Methods The clinical data of 100 patients with HCC admitted to our hospital from December 2019 to December 2022 were selected for retrospective analysis.All patients underwent pathological examination,VIM-DWI examination and MSCT examination.100 patients were diagnosed as MVI positive in 38 cases and MVI negative in 62 cases by surgical pathology.The differences in the analysis of qualitative and quantitative parameters of IVIM-DWI and MSCT between the two groups were compared,and the diagnostic value of quantitative parameters of IVIM-DWI,quantitative parameters of MSCT and combined data for the presence of MVI in HCC was analyzed by ROC curve.Results The MVIpositive group had higher marginal grossness,peritumoral low signal,peritumoral enhancement,and presence of halo sign than the MVI-negative group(P<0.05),and lower tumor envelope than the MVInegative group(P<0.05).There was no statistically significant difference between the two groups in D and F(P>0.05),but ADC and D were lower in the MVI-positive group than in the MVI-negative group(P<0.05).CT values in the arterial phase were lower in the MVI-positive group than in the MVI-negative group(P<0.05),and CT values in the delayed phase,CT values in the portal phase,and tumor size were higher than in the MVI-negative group(P<0.05).analysis of ROC curves showed that The AUCs of ADC,D,D,f,delayed phase CT value,portal vein phase CT value,arterial phase CT value,and tumor size for diagnosing HCC with MVI were 0.775,0.856,0.609,0.565,0.708,0.728,0.643,and 0.705,respectively.MSCT parameters,IVIM-DWI parameters,and combined data for diagnosing HCC The AUCs for the presence of MVI were 0.809,0.832,and 0.920,respectively,all with good accuracy.Conclusion IVIM-DWI and MSCT qualitative and quantitative parameters were correlated with MVI in HCC patie

关 键 词：肝细胞肝癌 体素内不相干运动扩散加权成像 多层螺旋CT 微血管侵犯 相关性 

分 类 号：R735.7[医药卫生—肿瘤]