磁共振加速器治疗局部晚期直肠癌的初步经验  

Magnetic resonance linac for locally advanced rectal cancer:a preliminary experience

作　　者：马慧颖 凡新苓 覃仕瑞 陈佳赟 曹莹 徐源 金晶 唐源 Ma Huiying;Fan Xinling;Tan Shirui;Chen Jiayun;Cao Ying;Xu Yuan;Jin Jing;Tang Yuan(Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital Chinese Academy of Medical Sciences and Peking Union Medical College,Shenzhen 518116,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021 [2]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院深圳医院放疗科,深圳518116

出　　处：《中华结直肠疾病电子杂志》2023年第6期519-523,共5页Chinese Journal of Colorectal Diseases(Electronic Edition)

基　　金：国家自然科学基金面上项目(No.82073352)。

摘　　要：磁共振加速器作为一种新型的放射治疗设备,应用于直肠癌的经验较少报道。本文介绍了磁共振加速器治疗直肠癌的步骤,并报告了使用该步骤治疗6例局部晚期直肠癌的初步治疗结果。6例直肠肿瘤均退缩,其中2例(2/6)可达肿瘤完全消退,所有患者放疗期间未出现3度以上毒副反应。每次放疗实施前,MR图像显示解剖、靶区清晰,可顺利实现在线自适应放疗和实时跟踪放疗。磁共振加速器在直肠癌放疗方面具有良好的应用前景。As an emerging radiation therapy modality,experience with magnetic resonance linac(MR-Linac)for rectal cancer is rarely reported.This article introduces a procedure for the treatment of rectal cancer with MR-Linac and reports the preliminary results of the treatment of 6 cases of locally advanced rectal cancer using this procedure.All of the rectal tumors regressed,with 2 cases(2/6)achieving complete tumor regression,and no≥G3 acute toxicities occurred during radiation therapy.Before the implementation of each radiotherapy,MR image shows the anatomy and target volume clearly,which can successfully realize online adaptive radiotherapy and real-time tracking radiotherapy.MR-linac has a good prospect in the radiotherapy of rectal cancer.

关 键 词：直肠肿瘤 放疗 磁共振加速器 

分 类 号：R735.37[医药卫生—肿瘤]