The clinical significance of human papillomavirus and p16^(INK4a)in vulvar tumors  

作　　者：Penglin Liu Zhuang Li Zhongshao Chen Zhaoyang Zhang Kun Song Jinwei Miao Beihua Kong 

机构地区：[1]Department of Gynecological Oncology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing,100006,China [2]Department of Obstetrics and Gynecology,Qilu Hospital of Shandong University,Jinan,Shandong,250012,China

出　　处：《Gynecology and Obstetrics Clinical Medicine》2023年第4期195-197,共3页妇产科临床医学（英文）

基　　金：supported by the Tai-Shan Scholar Program of Shandong Province (Code:ts20070743);Beijing Hospitals Authority's Ascent Plan (Code:DFL20221201).

摘　　要：Vulvar cancer is the fourth most common gynecological malignancy,with a global incidence of an estimated 45,240 new cases and 17,427 deaths in 2022.1 The 5-year survival rate for vulvar cancer is about 70%based on data from the SEER database.2 More than 90%of vulvar cancer was vulvar squamous cell carcinoma(SCC),which included keratinizing,non-keratinizing,basaloid,warty,and verrucous carcinoma.

关 键 词：Vulvar cancer Vulvar intraepithelial neoplasia Human papillomavirus p16^(INK4a) DIAGNOSIS PROGNOSIS 

分 类 号：R737.3[医药卫生—肿瘤]