Advances in ablative treatment for human papillomavirus related cervical pre-cancer lesions  

作　　者：Lili Xu Yanming Jiang Renfeng Zhao 

机构地区：[1]Department of Gynecology,The People's Hospital of Guangxi Zhuang Autonomous Region,Guangxi Academy of Medical Sciences,Nanning,530021,China

出　　处：《Gynecology and Obstetrics Clinical Medicine》2023年第4期213-219,共7页妇产科临床医学（英文）

基　　金：supported by the Guangxi Health Technologies Promotion Program (Project number:S2020071)。

摘　　要：HPV infection is the primary cause of cervical intraepithelial neoplasia(CIN),with persistent high-risk HPV infection being the leading factor in the development of cervical cancer.In addition to the application of large loop excision of the transformation zone(LLETZ)for the treatment of cervical pre-cancerous lesions,various ablative techniques,including thermal ablation,cryotherapy,carbon dioxide(CO_(2))laser therapy,and focused ultrasound therapy also play significant roles in the management of cervical intraepithelial neoplasia.This review presents a comprehensive overview of the pathophysiology of cervical HPV infection and discusses the ablative methods commonly used in clinical practice,along with their indication and contradiction,especially in women with high-grade squamous intraepithelial lesions.The aim is to identify safe and effective treatment strategies for treating cervical intraepithelial neoplasia,thereby avoiding under-or over-treatment,which may reduce the incidenceandprogr ssion of cervical cancer through timely diagnosis and treatment.

关 键 词：Ablative treatment Thermal ablation CRYOTHERAPY Cervical intraepithelial neoplasia Human papillomavirus 

分 类 号：R737.33[医药卫生—肿瘤]