Clinical value of the Toronto inflammatory bowel disease global endoscopic reporting score in ulcerative colitis  

作　　者：Xin-Yue Liu Zi-Bin Tian Li-Jun Zhang Ai-Ling Liu Xiao-Fei Zhang Jun Wu Xue-Li Ding 

机构地区：[1]Department of Gastroenterology,The Affiliated Hospital of Qingdao University,Qingdao 266003,Shandong Province,China [2]Department of Population and Quantitative Health Sciences(PQHS),School of Medicine,Case Western Reserve University,Cleveland,OH 44106,United States [3]Department of Gastroenterology,Qingdao Hospital,University of Health and Rehabilitation Sciences(Qingdao Municipal Hospital),Qingdao 266011,Shandong Province,China

出　　处：《World Journal of Gastroenterology》2023年第48期6208-6221,共14页世界胃肠病学杂志（英文版）

基　　金：Clinical Medicine+X Research Project of the Affiliated Hospital of Qingdao University in 2021,No.QDFY+X202101036;Qingdao Medical and Health Research Program in 2021,No.2021-WJZD166;and Youth Project of Natural Science Foundation of Shandong Province,No.ZR2020QH031.

摘　　要：BACKGROUND Endoscopic evaluation in diagnosing and managing ulcerative colitis(UC)is becoming increasingly important.Several endoscopic scoring systems have been established,including the Ulcerative Colitis Endoscopic Index of Severity(UCEIS)score and Mayo Endoscopic Subscore(MES).Furthermore,the Toronto Inflammatory Bowel Disease Global Endoscopic Reporting(TIGER)score for UC has recently been proposed;however,its clinical value remains unclear.AIM To investigate the clinical value of the TIGER score in UC by comparing it with the UCEIS score and MES.METHODS This retrospective study included 166 patients with UC who underwent total colonoscopy between January 2017 and March 2023 at the Affiliated Hospital of Qingdao University(Qingdao,China).We retrospectively analysed endoscopic scores,laboratory and clinical data,treatment,and readmissions within 1 year.Spearman’s rank correlation coefficient,receiver operating characteristic curve,and univariate and multivariable logistic regression analyses were performed using IBM SPSS Statistics for Windows,version 26.0(IBM Corp.,Armonk,NY,United States)and GraphPad Prism version 9.0.0 for Windows(GraphPad Software,Boston,Massachusetts,United States).RESULTS The TIGER score significantly correlated with the UCEIS score and MES(r=0.721,0.626,both P<0.001),showed good differentiating values for clinical severity among mild,moderate,and severe UC[8(4-112.75)vs 210(109–219)vs 328(219–426),all P<0.001],and exhibited predictive value in diagnosing patients with severe UC[area under the curve(AUC)=0.897,P<0.001].Additionally,the TIGER(r=0.639,0,551,0.488,0.376,all P<0.001)and UCEIS scores(r=0.622,0,540,0.494,and 0.375,all P<0.001)showed stronger correlations with laboratory and clinical parameters,including C-reactive protein,erythrocyte sedimentation rate,length of hospitalisation,and hospitalisation costs,than MES(r=0.509,0,351,0.339,and 0.270,all P<0.001).The TIGER score showed the best predictability for patients'recent advanced treatment,including systemic corticostero

关 键 词：Ulcerative colitis Toronto Inflammatory Bowel Disease Global Endoscopic Reporting score Ulcerative Colitis Endoscopic Index of Severity Mayo Endoscopic Subscore Endoscopy SEVERITY 

分 类 号：R574.62[医药卫生—消化系统]