Use of MLC901 in cerebral venous sinus thrombosis:Three case reports  

作　　者：Anita Ante Arsovska Narayanaswamy Venketasubramanian 

机构地区：[1]Department of Urgent Neurology,University Clinic of Neurology,University Ss.Cyril and Methodius-Faculty of Medicine,Skopje 1000,North Macedonia [2]Department of Neurology,Raffles Hospital,Singapore 188770,Singapore

出　　处：《World Journal of Clinical Cases》2024年第2期346-353,共8页世界临床病例杂志

摘　　要：BACKGROUND Cerebral venous sinus thrombosis(CVT)is rare cause of cerebrovascular disease.The incidence is 0.5%of all stroke.The majority of affected patients are young adults(mean age:35-40 years)with mild to moderate disabilities.Poor outcome with severe disability is seen in 13%of cases.Early diagnosis and treatment are important for good outcomes and preventing complications.Treatment options are limited and mostly based on consensus.NeuroAiD II™(MLC901;Moleac Pte,Ltd,Singapore)has a potential beneficial role in post-stroke recovery,by aiding the natural brain recovery process.CASE SUMMARY MLC901 consists of nine natural herbal ingredients.Studies have shown its safety profile and aid in post stroke recovery.The aim of this case series was to demonstrate the potential role of MLC901 in stroke recovery of patients with cerebral venous sinus thrombosis(CVST)who received MLC901 in addition to standard of care.The prescribed dose of MLC901 is 400 mg/cap two capsules,three times a day.Data from these patients were prospectively collected at baseline and at monthly visits,for a duration of 3 mo.Outcome measures included adherence to therapy,side effects,National Institutes of Health Stroke Scale,Glasgow Coma Scale,modified Rankin Scale,and the Short Orientation-Memory-Concentration Test.MLC901 was well tolerated and no side effects were reported.All patients were stable with improved condition.CONCLUSION This case series highlights the potential therapeutic effects of MLC901 on CVST and provides support for further studies.

关 键 词：MLC901 Cerebral venous sinus thrombosis Anticoagulation therapy SAFETY Case report 

分 类 号：R743.32[医药卫生—神经病学与精神病学]