急性前循环大血管闭塞性脑梗死桥接治疗和单纯机械取栓治疗的临床疗效  

Clinical Efficacy of Bridging Therapy and Mechanical Thrombolysis Alone in Acute Anterior Circulation LargeVessel Occlusion Cerebral Infarction

作　　者：王晓丽[1] 秦晋辉 Wang Xiaoli;Qin Jinhui(Department of Cerebrovascular Interventions,Nanyang Second People’s Hospital,Nanyang,Henan,473000,China)

机构地区：[1]南阳市第二人民医院脑血管介入科,河南南阳473000

出　　处：《黑龙江医学》2024年第2期156-158,共3页Heilongjiang Medical Journal

摘　　要：目的:比较桥接治疗和单纯机械取栓治疗在急性前循环大血管闭塞性脑梗死中的临床疗效。方法:选取2021年1月—2022年1月南阳市第二人民医院脑血管介入科收治的50例急性前循环大血管闭塞性脑梗死患者作为研究对象,根据手术方案不同,分成桥接组(n=25)和单纯机械取栓组(n=25)。比较血管再通情况、取栓相关指标、神经功能恢复情况、预后情况、并发症发生率。结果:两组患者血管再通情况、血管再通等级比较,差异无统计学意义(Z=-0.623,P>0.05)。两组患者取栓次数和术后再灌注情况比较,差异无统计学意义(t=0.244;χ^(2)=0.095,P>0.05)。手术后,两组患者美国国立卫生研究院卒中量表(NIHSS)、入院时改良Rankin(m RS)评分比较,差异无统计学意义(t=0.034、0.415,P>0.05)。单纯机械取栓组患者并发症发生率情况低于桥接组,差异有统计学意义(χ^(2)=4.153,P<0.05)。结论:手术治疗急性前循环大血管闭塞性脑梗死,选择桥接治疗和单纯机械取栓治疗均有很好的临床疗效,疗效相当。单纯机械取栓能够降低术中出血转化发生率,取得理想预后。Objective:To compare the clinical effects of bridging therapy and mechanical embolectomy in acute anterior circulation cerebral infarction.Methods:50 patients with acute anterior circulation large-vessel occlusive cerebral infarction admitted to the hospital from January 2021 to January 2022 were selected for the study,and were divided into the bridging group(n=25)and the pure mechanical thrombolysis group(n=25)according to the different surgical protocols.The revascularization,embolization-related indexes,neurological recovery,prognosis,and complication rates were compared.Results:There was no statistically significant difference between the two groups in terms of revascularization and grade of revascularization(Z=-0.623,P>0.05).There was no statistically significant difference in the number of embolization and postoperative reperfusion between the two groups(χ^(2)/t=0.244,0.095,P>0.05).After surgery,there was no statistically significant difference between the NIHSS and mRS score groups of the two groups(t=0.034,0.415,P>0.05).The complication rate situation of patients in the mechanical thrombus extraction alone group was lower than that of the bridging group,and the difference was statistically significant(χ^(2)=4.153,P<0.05).Conclusion:Surgical treatment of acute anterior circulation large-vessel occlusive cerebral infarction,the choice of bridging therapy and mechanical thrombolysis alone both have excellent clinical efficacy and comparable efficacy.Mechanical thrombolysis alone can reduce the incidence of intraoperative hemorrhagic transformation and achieve an ideal prognosis.

关 键 词：急性前循环大血管闭塞性脑梗死 桥接 单纯机械取栓 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]