全身磁共振弥散加权成像联合多层螺旋CT对多发性骨髓瘤的诊断价值  

Diagnostic value of whole body magnetic resonance diffusion weighted imaging combined with multi-slice spiral CT in multiple myeloma

作　　者：黄雪莹[1] 党佩 杨瑞[2] 田博[1] 王晓东[1] HUANG Xueying;DANG Pei;YANG Rui;TIAN Bo;WANG Xiaodong(Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Hematology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院放射科,宁夏银川750004 [2]宁夏医科大学总医院血液科,宁夏银川750004

出　　处：《分子影像学杂志》2024年第1期47-51,共5页Journal of Molecular Imaging

基　　金：宁夏回族自治区重点研发计划(科技支撑)项目(2019BEG03037)。

摘　　要：目的 探究全身磁共振弥散加权成像(WB-DWI)联合多层螺旋CT对多发性骨髓瘤的诊断价值。方法 选取2019年6月~2023年1月于我院收治的80例多发性骨髓瘤患者为研究对象,并按照检测方式将其分为WB-DWI组(n=25)、多层螺旋CT组(n=25)、联合组(n=30)。分析WB-DWI、多层螺旋CT单一及联合对患者累及部位的检出率,分析两种检查方式单一及联合对多发性骨髓瘤的检出情况,通过ROC曲线分析WB-DWI、多层螺旋CT联合诊断多发性骨髓瘤的临床价值。结果 检测结果主要与Durie-Salmon分期、国际骨髓瘤分期相关(P<0.05)。与WB-DWI、多层螺旋CT单一检测对比,联合检测患者累及部位的检出率较高(P<0.05)。在多发性骨髓瘤诊断中WB-DWI、多层螺旋CT联合检测高于单一检测(P<0.05)。与WB-DWI、多层螺旋CT单项诊断对比,两项联合诊断多发性骨髓瘤的敏感度、特异性、准确性均较高(P<0.05)。结论 相较于WB-DWI、多层螺旋CT单项检测,联合检测可有效提升患者病理检出情况,提高对多发性骨髓瘤的诊断价值。Objective To explore the diagnostic value of whole body magnetic resonance diffusion weighted imaging(WB-DWI)combined with multi-slice spiral CT in multiple myeloma.Methods A total of 80 patients with multiple myeloma admitted to our hospital from June 2019 to January 2023 were selected as study subjects and divided into WB-DWI group(n=25),multi slice spiral CT group(n=25)and combined group(n=30).The detection rates of WB-DWI and multi-slice spiral CT alone and combined in the involved sites of patients were analyzed,and the detection of multiple myeloma by the two methods alone and combined was analyzed.The clinical value of WB-DWI and multi-slice spiral CT combined in the diagnosis of multiple myeloma was analyzed by ROC curve.Results The results were mainly correlated with Durie-Salmon stage and international myeloma stage(P<0.05).Compared with the single detection of WB-DWI and multi-slice spiral CT,the detection rate of the involved sites in the combined detection was higher(P<0.05).The combined detection of WB-DWI and multi-slice spiral CT was higher than that of single detection in the diagnosis of multiple myeloma(P<0.05).Compared with the single diagnosis of WB-DWI and multi-slice spiral CT,the sensitivity,specificity and accuracy of the combined diagnosis of multiple myeloma were higher(P<0.05).Conclusion Compared with WB-DWI and multi-slice spiral CT single tests,the combined test can effectively improve the pathological detection of patients and improve the diagnostic value of multiple myeloma.

关 键 词：多发性骨髓瘤 全身磁共振弥散加权成像 多层螺旋CT 国际肿瘤分期 

分 类 号：R733.3[医药卫生—肿瘤] R445.2[医药卫生—临床医学] R730.44