Preparation and characterization of pH-responsive metal-polyphenol structure coated nanoparticles  

作　　者：Qile Xia Yan Liang Ailing Cao Yan Cao Luyun Cai 

机构地区：[1]Key Laboratory of Post-Harvest Handling of Fruits,Food Science Institute,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China [2]Ningbo Research Institute,College of Biosystems Engineering and Food Science,Zhejiang University,Ningbo 315100,China [3]School of Biological and Chemical Engineering,Zhejiang Engineering Research Center for Intelligent Marine Ranch Equipment,NingboTech University,Ningbo 315100,China [4]College of Food Science and Engineering,Bohai University,Jinzhou 121013,China [5]Hangzhou Customs District,Hangzhou 310007,China

出　　处：《Food Science and Human Wellness》2024年第3期1303-1310,共8页食品科学与人类健康（英文）

基　　金：supported by the National Key R&D Program of China (2018YFD0901106);the Wenzhou Major Science and Technology Project (ZN2021002);the Ningbo“3315 series program”for high-level talents (2020B-34-G)。

摘　　要：In this paper,tannic acid(TA)and Fe~(3+)were added to form a layer of metal-polyphenol network structure on the surface of the nanoparticles which were fabricated by zein and carbon quantum dots(CQDs)encapsulating phlorotannins(PTN).pH-Responsive nanoparticles were prepared successfully(zein-PTN-CQDs-Fe-~Ⅲ).Further,the formation of composite nanoparticles was confirmed by a series of characterization methods.The zeta-potential and Fourier transform infrared spectroscopy data proved that electrostatic interaction and hydrogen bonding are dominant forces to form nanoparticles.The encapsulation efficiency(EE)revealed that metal-polyphenol network structure could improve the EE of PTN.Thermogravimetric analysis and differential scanning calorimetry experiment indicated the thermal stability of zein-PTN-CQDs-Fe~Ⅲnanoparticles increased because of metal-polyphenol network structure.The pH-responsive nanoparticles greatly increased the release rate of active substances and achieved targeted release.

关 键 词：METAL PHLOROTANNINS NANOPARTICLES PH-RESPONSIVE CHARACTERIZATION 

分 类 号：TS201.2[轻工技术与工程—食品科学] TB383.1[轻工技术与工程—食品科学与工程]