Characterization of mulberry leaf instant tea and evaluation of its hypolipidemia effect via regulation of intestinal microbiota  

作　　者：Xiaoyun Han Yunlong Bai Xiaoxin Feng Baochang Du Baojiang Zheng Qingshen Sun 

机构地区：[1]Engineering Research Center of Agricultural Microbiology Technology,Ministry of Education&Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region,Key Laboratory of Molecular Biology&Key Laboratory of Microbiology,College of Heilongjiang Province&School of Life Sciences,Heilongjiang University,Harbin 150080,China [2]Gannan Forest Farm,Qiqihaer 162100,China [3]College of Life Sciences,Northeast Forestry University,Harbin 150040,China

出　　处：《Food Science and Human Wellness》2024年第3期1348-1357,共10页食品科学与人类健康（英文）

基　　金：supported by the Natural Science Foundation of Heilongjiang Province (LH2021C075);Key Laboratory of Functional Inorganic Material Chemistry (Heilongjiang University),Ministry of Education。

摘　　要：The purpose of this study was to characterize mulberry leaf instant tea(MLIT)powder prepared from the'Longsang No.1'(Morus abla L.cv.Longsang 1)mulberry leaves in Heilongjiang Province(China)and assess its obesity-preventing/relieving effects.A total of 174 compounds including quercetin,chlorogenic acid,1-deoxyecomycin(1-DNJ)related to antihyperlipidemia effects were identified from the MLIT powder.MLIT treatment reversed the Lee's index,fat coefficient,and serum biochemical parameters in both the obesity relieving and obesity preventing mice fed with high-fat diet.In the obesity relieving experiment,the relative abundance of Desulfovibrio in mouse feces decreased after both 0.5%and 1%MLIT treatments.In obesity preventing experiments,mouse with different amount of MLIT treatments showed increased relative abundance of Akkermansia,Bifidobacterium and Lactobacillus,while Deferribacteres,Desulfobacterota decreased.The beneficial bacteria in the intestinal tract of mice treated with MLIT increased.This study proved that MLIT had antihyperlipidemia potential via modulating intestinal microbiota in mice.

关 键 词：Mulberry leaf instant tea Liquid chromatography-mass spectrometry(LC-MS) Antihyperlipidemia Intestinal microbiota 

分 类 号：TS272.5[农业科学—茶叶生产加工]