The in vitro digestion fates of diacylglycerol under different intestinal conditions:a potential lipid source for lipid indigestion patients  

作　　者：Qingqing Xu Weifei Wang Dongxiao Sun-Waterhouse Qian Zou Menglei Yan Xuan Liu Dongming Lan Yonghua Wang 

机构地区：[1]School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,China [2]Sericultural and Agri-Food Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610,China [3]School of Chemical Sciences,The University of Auckland,Private Bag 92019,New Zealand [4]Guangdong Youmei Institute of Intelligent Bio-manufacturing Co.,Ltd.,Foshan 528200,China

出　　处：《Food Science and Human Wellness》2024年第2期1079-1092,共14页食品科学与人类健康（英文）

基　　金：National Key R&D Program of China(2022YFC2805100);National Science Fund for Key Program of National Natural Science Foundation of China(31930084);National Science Fund for Distinguished Young Scholars of China(31725022);China Agriculture Research System(CARS-18-ZJ0503);Guangdong Provincial Key R&D Programme(2022B0202010002);Science and Technology Innovation Project of Foshan City(FS0AAKJ919-4402-0013)。

摘　　要：The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diacylglycerols(DAGs)are potential good lipid sources for these patients.Linseed oil-based DAG(LD)and linseed oil(LT)were selected.LD-based emulsion((83.74±1.23)%)had higher lipolysis degree than LT-based emulsion((74.47±1.16)%)when monitoring the GI tract of normal population as previously reported.Indigestion conditions seriously decreased the digestive degree of LT-based emulsion((40.23±2.48)%-(66.50±3.70)%)while showed less influence on LD-based emulsion((64.18±2.41)%-(81.85±3.45)%).As opposed to LT-based emulsion,LD-based emulsion exhibited preference for releasing unsaturated fatty acids(especially oleic acid andα-linolenic acid)due to their different glycerolipid compositions.LD-based emulsion showed potential for providing lipids and nutrients(including essential fatty acids)for lipid indigestion patients.

关 键 词：DIACYLGLYCEROL In vitro digestion Lipolysis level Cholestatic Exocrine pancreatic insufficiency 

分 类 号：TS201.4[轻工技术与工程—食品科学]