基于腹部计算机断层扫描与气体容积积分检测功能性消化不良患者胃肠道气体量的比较研究  

A comparative study of gastrointestinal gas volume in patients with functional dyspepsia based on abdominal computed tomography and gas volume score

作　　者：王彬[1] 赵威[1] 张莉莉[1] 晋弘[1] 陈鑫[1] 汪毅[2] 王邦茂[1] Wang Bin;Zhao Wei;Zhang Lili;Jin Hong;Chen Xin;Wang Yi;Wang Bangmao(Department of Gastroenterology and Hepatology,Tianjin Medical University General Hospital,Tianjin Institute of Digestive Diseases,Tianjin Key Laboratory of Digestive Diseases,Tianjin 300052,China;School of Precision Instrument and Opto-Electronics Engineering,Tianjin University,Tianjin 300073,China)

机构地区：[1]天津医科大学总医院消化内科、天津市消化疾病研究所、天津市消化病学重点实验室,天津300052 [2]天津大学精密仪器与光电子工程学院,天津300073

出　　处：《中华消化杂志》2023年第10期677-682,共6页Chinese Journal of Digestion

基　　金：天津市应用基础研究项目(20JCYBJC00450、21JCQNJC01130、20JCQNJC00560)。

摘　　要：目的比较基于气体容积积分(GVS)法与计算机断层扫描(CT)图像联合计算公式法(以下简称CT法)检测功能性消化不良(FD)患者胃肠道气体量的差异。方法纳入2021年12月1日至2022年6月30日于天津医科大学总医院消化内科门诊就诊的FD患者27例(FD组),同期选择天津医科大学总医院体检中心数据库的健康对照者30例(健康对照组),两组患者均同时完善立位腹部X线和全腹部CT检查。分别运用GVS法和CT法计算并比较两组患者,以及FD亚型[餐后不适综合征(PDS)型、上腹痛综合征(EPS)型、PDS重叠EPS型]患者间的胃肠道气体量。统计学方法采用独立样本t检验和单因素方差分析。结果基于GVS法,FD组胃腔、小肠、结直肠气体量分别为0.04±0.01、0.06±0.01、0.06±0.01,健康对照组分别为0.04±0.01、0.05±0.01、0.05±0.01,FD组的小肠和结直肠气体量高于健康对照组,差异均有统计学意义(t=3.48、4.40,P=0.001、<0.001);PDS型、EPS型、PDS重叠EPS型3个FD亚型患者的胃腔、小肠、结直肠气体量分别为0.04±0.01、0.04±0.01、0.05±0.00,0.06±0.01、0.06±0.01、0.05±0.00,0.06±0.01、0.06±0.01、0.06±0.01,各亚型间的胃腔、小肠和结直肠气体量差异均无统计学意义(均P>0.05)。基于CT法,FD组胃腔、小肠、结直肠气体量分别为(17090.89±4437.40)、(32597.53±7865.86)、(49010.20±12972.42)mm^(3),健康对照组胃腔、小肠、结直肠气体量分别为(13424.43±5211.86)、(33567.93±9157.23)、(39036.22±6343.27)mm^(3);FD组的胃腔和结直肠气体量高于健康对照组,差异均有统计学意义(t=2.84、3.75,P=0.006、0.001);PDS型、EPS型、PDS重叠EPS型3个FD亚型患者的胃腔、小肠、结直肠气体量分别为(18464.03±4088.57)、(14560.97±3771.26)、(16806.17±4299.60)mm^(3),(31820.79±7022.77)、(30604.84±8343.10)、(37140.05±8276.58)mm^(3),(47447.66±14047.00)、(49645.73±9527.73)、(51181.96±16836.97)mm^(3),PDS型患者的胃腔气体量高于EPS型,差异Objective To compare the difference between gas volume score(GVS)method and combination of computed tomography(CT)image and calculation formula method(hereinafter referred to as CT method)in the detection of gastrointestinal gas volume in functional dyspepsia(FD)patients.Methods From December 1,2021 to June 30,2022,27 FD patients(FD group)who visited the Department of Gastroenterology and Hepatology of Tianjin Medical University General Hospital were enrolled.At the same period,30 healthy controls were selected from the database of check-up center as the healthy control group.All the participants of the two groups underwent erect plain abdominal X-ray and abdominal CT scan.The GVS and CT methods were used to calculate and compare gastrointestinal gas volume between two groups of patients,as well as patients with FD subtypes(postprandial distress syndrome(PDS),epigastric pain syndrome(EPS),and PDS overlapping with EPS).Independent sample t-test and one-way ANOVA were used for statistical analysis.Results Based on the GVS method,the gas volume of gastric cavity,small intestine and colorectum of FD group were 0.04±0.01,0.06±0.01 and 0.06±0.01,respectively;and those of the healthy control group were 0.04±0.01,0.05±0.01 and 0.05±0.01,respectively.The gas volume of small intestine and colorectum of FD group were higher than those of the healthy control group,and the differences were statistically significant(t=3.48 and 4.40,P=0.001 and<0.001).The gas volume of gastric cavity,small intestine and colorectum of FD patients with subtypes of PDS,EPS,and PDS overlapping with EPS were 0.04±0.01,0.04±0.01 and 0.05±0.00,0.06±0.01,0.06±0.01 and 0.05±0.00,and 0.06±0.01,0.06±0.01 and 0.06±0.01,respectively.There were no significant difference in the gas volume of gastric cavity,small intestine and colorectum among different subtypes(all P>0.05).Based on the CT method,the gas volume of gastric cavity,small intestine and colorectum of FD group were(17090.89±4437.40)mm^(3),(32597.53±7865.86)mm^(3) and(49010.20±12972

关 键 词：功能性消化不良 胃肠道气体 腹部计算机断层扫描 气体容积积分 

分 类 号：R57[医药卫生—消化系统]