2003—2019年上海市嘉定区结直肠癌流行趋势研究  

Epidemic Trend Analysis of Colorectal Cancer in Jiading District,Shanghai from 2003 to 2019

作　　者：陈单 王亚伟 黄芳[2] 徐一凡 张一英[2] 邵月琴[2] CHEN Dan;WANG Yawei;HUANG Fang;XU Yifan;ZHANG Yiying;SHAO Yueqin(School of Public Health,Fudan University,Shanghai 200032,China;Jiading district Center for Disease Control and Prevention,Shanghai 201800,China)

机构地区：[1]复旦大学公共卫生学院,上海市200032 [2]上海市嘉定区疾病预防控制中心,201800

出　　处：《中国全科医学》2024年第10期1261-1266,共6页Chinese General Practice

摘　　要：背景结直肠癌已成为上海市嘉定区发病率排名第三的恶性肿瘤,其疾病负担仍在加重。目的分析2003—2019年上海市嘉定区结直肠癌流行趋势,为结直肠癌防治提供科学依据。方法基于2003—2019年上海市嘉定区肿瘤登记资料,计算粗发病率、粗死亡率、标化发病率、标化死亡率等统计指标(以2010年中国标准人口构成进行标化调整),利用Joinpoint Regression Program 4.9.1.0软件分析发病率和死亡率的变化趋势。结果2003—2019年上海市嘉定区结直肠癌新发病例5020例,粗发病率52.12/10万,标化发病率26.27/10万,死亡病例2419例,粗死亡率25.12/10万,标化死亡率11.16/10万,男性的粗发病率和粗死亡率均高于女性(P<0.05);总人群标化发病率总体呈现上升趋势(APC=2.63%,P<0.05),其中男性标化发病率呈上升趋势(APC=3.48%,P<0.05),女性标化发病率无明显变化趋势(APC=1.39%,P=0.119),均未发现转折点;总人群标化死亡率无明显变化趋势(APC=-0.49%,P=0.250),其中男性标化死亡率无明显变化趋势(APC=0.34%,P=0.545),女性标化死亡率呈现下降趋势(APC=-1.94%,P<0.05)。结论2003—2019年上海市嘉定区结直肠癌总体发病率总体仍有上升,其中男性呈上升趋势,女性无明显变化趋势;总体死亡率无明显变化趋势,其中男性无明显变化,女性呈下降趋势,应继续加强结直肠癌的防控工作,重点关注男性人群。Background Colorectal cancer has become the third most prevalent malignant tumor in Jiading district of Shanghai,and its disease burden is still increasing.Objective To analyze the epidemic trend of colorectal cancer in Jiading district of Shanghai from 2003 to 2019 and provide scientific basis for the prevention and treatment of colorectal cancer.Methods Based on the cancer registration data from 2003 to 2019 in Jiading district of Shanghai,the statistical indicators such as crude incidence rate,crude mortality rate,standardized incidence rate and standardized mortality rate were calculated(the rate was standardized using the Chinese standard population of 2010).Joinpoint Regression Program 4.9.1.0 software was used to analyze the trends of incidence rate and mortality rate.Results From 2003 to 2019,there were 5020 new cases of colorectal cancer in Jiading district of Shanghai,with a crude incidence rate of 52.12/100000,a standardized incidence rate of 26.27/100000;there were 2419 deaths,with a crude mortality rate of 25.12/100000,and a standardized mortality rate of 11.16/100000;with males having higher crude incidence and crude mortality rates than females(P<0.05).There was an overall upward trend in the total population standardized incidence rate(APC=2.63%,P<0.05),with an increasing trend in the male standardized incidence rate(APC=3.48%,P<0.05),and no significant trend in the female standardized incidence rate(APC=1.39%,P=0.119),while no turning point was found.There was no significant trend in the total population standardized mortality rate(APC=-0.49%,P=0.250),of which there was no significant trend in the male standardized mortality rate(APC=0.34%,P=0.545),and a decreasing trend in the female standardized mortality rate(APC=-1.94%,P<0.05).Conclusion From 2003 to 2019,the overall incidence rate of colorectal cancer in Jiading district of Shanghai still increased,among which there was an upward trend in males and no significant change in the trend for females.There was no significant trend in the overall m

关 键 词：结直肠肿瘤 发病率 死亡率 趋势 Joinpoint回归模型 上海市 

分 类 号：R735.34[医药卫生—肿瘤]