微生态调节剂对大负荷运动下肠道微生物群调节作用的研究进展  

Research progress in the regulation of gut microbiome by microbioecologics with heavy-load exercise

作　　者：王明涵 元宇[1] 宋昂芯 翁锡全[1] 毛钰蘅 WANG Ming-Han;YUAN Yu;SONG Ang-Xin;WENG Xi-Quan;MAO Yu-Heng(College of Sports and Health,Guangzhou Sport University,Guangzhou 510500,China;College of Brewing and Food Engineering,Guizhou University,Guiyang 550025,China)

机构地区：[1]广州体育学院运动与健康学院,广州510500 [2]贵州大学酿酒与食品工程学院,贵阳550025

出　　处：《生命科学》2023年第12期1639-1651,共13页Chinese Bulletin of Life Sciences

基　　金：广东省自然科学基金-面上项目(2023A1515010004);国家自然科学基金青年科学基金项目(82003434,81901430)。

摘　　要：大负荷运动不仅会使运动系统如骨骼、骨骼肌等受到影响,还可导致消化系统出现功能障碍,包括肠道微生物群失调、微生物多样性降低、肠屏障功能损伤等问题。而益生菌、益生元等微生态调节剂则可以对肠屏障功能、肠道微生物群等起到积极的调节作用,降低大负荷运动所引起的不良影响,提高恢复能力,进而提高运动表现。这提示微生态调节剂作为营养补剂在运动营养领域中具有重要的应用前景。该文对大负荷运动影响肠道微生物群及其作用机制进行介绍,并梳理益生菌、益生元等微生态调节剂对肠道微生物群的调节作用。Heavy-load exercise not only affects skeletal system,including bones,skeletal muscle etc.,but also leads to dysfunction of digestive system,including intestinal microbiome imbalance,microbial diversity reduction,intestinal barrier function damage and other problems.Meanwhile,probiotics,prebiotics and other microecological regulators are able to positively regulate intestinal barrier function and intestinal microbiota,alleviate the adverse effects induced by heavy load exercise,improve recovery ability,and further improve exercise performance.These results suggest that microecologics as nutritional supplements in the field of sports nutrition has an important application prospects.This paper introduced the adverse effects and the related mechanisms induced by heavy-load exercise on gut microbiome,and reviewed the regulatory effects of probiotics,prebiotics and other microecological regulators on gut microbiome.

关 键 词：肠道微生物群 运动营养 肠屏障功能 微生态调节剂 

分 类 号：Q939[生物学—微生物学]