儿童首次非诱发性癫痫发作后的检查治疗及管理:三十余年来的变化与挑战  

Workup,treatment and management of a first unprovoked seizure in children:changes and challenges over the past 30 years

作　　者：胡春辉 林滨榕[1] 周有峰 HU Chunhui;LIN Binrong;ZHOU Youfeng(Department of Neurology,Fujian Children’s Hospital(Fujian Branch of Shanghai Children's Medical Center),National Regional Medical Center,College of Clinical Medicine for Obstetrics&Gynecology and Pediatrics,Fujian Medical University,Fuzhou 350014,China)

机构地区：[1]福建医科大学妇儿临床医学院·国家区域医疗中心·福建省儿童医院(上海儿童医学中心福建医院)神经内科,福州350014

出　　处：《癫痫杂志》2024年第1期73-77,共5页Journal of Epilepsy

摘　　要：癫痫和癫痫发作长期以来有着共同的污名化历史,在近20世纪,癫痫患者才与精神障碍和神经退行性疾病患者一起被常规治疗。30余年前,学者们还一直认为绝大多数首次非诱发性癫痫发作的患者,除非接受治疗,否则会出现更多的癫痫发作。直到Hauser研究报道,才发生了里程碑式的变化。然而针对首次非诱发性癫痫发作后的检查治疗,依然争论不止,未达成共识。本文旨在对近30余年来,儿童首次非诱发性癫痫发作后的检查治疗及管理中的变化与挑战作一综述,旨在提供可用数据及规范化管理流程。Epilepsy and epileptic seizures have a long history of stigmatization.In the 20th century,epilepsy patients were treated as usual as patients with mental disorders and neurodegenerative diseases.More than 30 years ago,scholars still believed that most patients with a first unprovoked seizure would have more seizures unless they were treated.It was not taken place until Hauser's research reported that landmark changed.However,there is still controversy about workup and treatment for a first unprovoked seizure.No consensus was reached.This article is to review the changes and challenges in the workup,treatment and management of a first unprovoked seizure in children in the past 30 years in order to provide available data and standardized management process.

关 键 词：癫痫 首次非诱发性癫痫发作 检查 治疗 管理 

分 类 号：R742.1[医药卫生—神经病学与精神病学]