卡波西肉瘤治疗研究新进展  

Treatment of Kaposi′s sarcoma

作　　者：高艳 王鹏[1] 康晓静[1] Gao Yan;Wang Peng;Kang Xiaojing(Department of Dermatology,People′s Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830001,China)

机构地区：[1]新疆维吾尔自治区人民医院皮肤科,新疆皮肤病研究重点实验室(XJYS1707),乌鲁木齐830001

出　　处：《中华皮肤科杂志》2024年第1期85-89,共5页Chinese Journal of Dermatology

基　　金：新疆维吾尔自治区创新环境(人才、基地)建设专项"天山创新团队计划"项目(2020D14006)。

摘　　要：卡波西肉瘤(KS)的发生与KS相关疱疹病毒(KSHV)感染内皮细胞密切相关.感染KSHV后可表现为各种类型KS,不同分型的临床特点、病情严重程度及预后各有差异.经典型病变局限、病情发展缓慢,艾滋病相关型、地方型侵袭性强,医源型在治疗的同时需控制原发病.应根据KS的临床分型及临床特点制定个体化治疗方案.本文综述KS的治疗方案及研究进展.The occurrence of Kaposi′s sarcoma(KS)is closely related to Kaposi′s sarcoma-associated herpesvirus(KSHV)infection of endothelial cells.KSHV infection can present as various types of KS,and clinical features,severity and prognosis differ among different types of KS.Classic KS is characterized by localized lesions and slow progression,AIDS-related KS and endemic KS are highly aggressive,and iatrogenic KS needs control of the primary disease during treatment.Therefore,individualized therapies should be developed according to the clinical classifications and characteristics of KS.This review summarizes treatment modalities of and research progress in KS.

关 键 词：肉瘤 卡波西 药物疗法 生物疗法 抗逆转录病毒治疗 高效 

分 类 号：R739.5[医药卫生—肿瘤]