基于文献计量学的针灸调节突触可塑性研究领域知识图谱可视化分析  

Knowledge Map of Acupuncture Regulating Synaptic Plasticity:A Bibliometric Analysis

作　　者：冯楚文 屈媛媛 孙忠人[3] 孙维伯 王铁刚[3,5] 杨添淞 FENG Chuwen;QU Yuanyuan;SUN Zhongren;SUN Weibo;WANG Tiegang;YANG Tiansong(The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Heilongjiang Provincial Key Laboratory of Informatics of Traditional Chinese Medicine,Harbin 150040,China;Heilongjiang University of Chinese Medicine,Harbin 150040,China;Harbin Medical University,Harbin 150040,China;Daqing Traditional Chinese Medicine Hospital,Heilongjiang 163311,China)

机构地区：[1]黑龙江中医药大学附属第一医院,哈尔滨150040 [2]黑龙江省中医药信息学重点实验室,哈尔滨150040 [3]黑龙江中医药大学,哈尔滨150040 [4]哈尔滨医科大学,哈尔滨150040 [5]大庆市中医医院,黑龙江大庆163311

出　　处：《神经损伤与功能重建》2024年第1期21-27,共7页Neural Injury and Functional Reconstruction

基　　金：国家自然科学基金(艾灸激活CaMKⅡ磷酸化介导长时程增强调节突触可塑性治疗CFS认知障碍的机制研究No.82305394;电针调控MDM2泛素化PSD-95水平重塑海马神经元突触结构改善CFS认知功能障碍的机制研究No.82074539);黑龙江省自然科学基金优秀青年项目(艾灸调节CaMKⅡ介导的LTP改善CFS认知障碍的机制研究No.YQ2023H019);黑龙江省中医药科研课题(电针调节CFS认知功能障碍大鼠海马突触可塑性的作用机制研究No.ZHY2022-136);黑龙江省中医药学会青年人才托举工程项目(“通督御疲调神针法”改善CFS认知功能障碍海马突触可塑性的效应机制研究No.2022-QNRC1-05)。

摘　　要：目的:基于文献计量学探讨近20年针灸调节突触可塑性的研究现状、热点及发展趋势。方法:以2002~2022年期间发表于CNKI的针灸调节突触可塑性实验研究为文献来源,应用CiteSpace和VOSviewer软件对作者、机构及关键词进行可视化分析。结果:纳入文献169篇,来源于73种期刊,《针刺研究》发文量最高;涉及作者421位,以孔立红为代表;研究机构148家,以福建中医药大学为代表;关键词325个,电针出现频次最高;关键词聚类效果显著,主要包括针灸调节突触可塑性的干预手段、研究疾病、作用靶点及机制;近年来突现词聚焦于针药结合、认知功能、长时程增强,且持续性可观。结论:近20年我国针灸调节突触可塑性研究领域发展迅速,已形成相对稳定的研究团队及研究方向。Objective:To explore current status,hot spots and development trends of acupuncture in the regulating of synaptic plasticity in the past 20 years based on bibliometrics.Methods:Experimental studies on the regulation of synaptic plasticity by acupuncture published in CNKI from 2002 to 2022 were cited as the literature source,CiteSpace and VOSviewer software were used to visually analyze authors,institutions and keywords.Results:A total of 169 studies were included.The studies came from 73 journals,and the number of articles published in Acupuncture Research was the highest.There were 421 authors involved,with Kong Lihong as the representative;148 research institutions,represented by Fujian University of Traditional Chinese Medicine;325 keywords,EA appeared most frequently.The clustering of keywords was significant,mainly including intervention methods,research diseases,targets and mechanisms of acupuncture in regulating synaptic plasticity.In recent years,emergent words have focused on the combination of acupuncture and medicine,cognitive function,and long-term potentiation,with significant persistence.Conclusion:In the past 20 years,the research field of acupuncture in regulating synaptic plasticity in China has developed rapidly,and a relatively stable research team and research direction have been formed.

关 键 词：针灸 突触可塑性 可视化分析 知识图谱 CITESPACE VOSviewer 

分 类 号：R741[医药卫生—神经病学与精神病学] R741.02[医药卫生—临床医学]