斑块内新生血管分级与颈动脉粥样硬化程度相关性的新进展  

New progress on the relationship between the grade of intraplaque neovascularization and the degree of carotid atherosclerosis

作　　者：范佳煜 董亚男 白竹(综述)[1] 陈盈[1] 王丽娟(审校)[1] FAN Jiayu;DONG Yanan;BAI Zhu(Neurology and Neuroscience Center,The First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院神经内科和神经科学中心,吉林长春130021

出　　处：《中风与神经疾病杂志》2024年第1期31-34,F0003,共5页Journal of Apoplexy and Nervous Diseases

基　　金：国家自然科学基金(82102066);吉林省自然科学基金项目(YDZJ202201ZYTS139);吉林省科技厅(20230508100RC);吉林科技厅自然科学基金项目(20210101254JC)。

摘　　要：颈动脉粥样硬化是导致缺血性事件发生的重要危险因素。颈动脉斑块负荷及颈动脉狭窄均与缺血性事件发生密切相关,此外,颈动脉斑块内成分也与缺血性事件发生息息相关。斑块内新生血管(intraplaque neovascularization,IPN)作为易损斑块的特征成分,通过多种机制参与颈动脉粥样斑块形成。本篇综述重点关注IPN分级与颈动脉粥样硬化程度的关系。Carotid atherosclerosis is an important risk factor leading to ischemic events.Carotid plaque load and carotid artery stenosis are closely related to the occurrence of ischemic events.In addition,the composition of carotid artery plaques is also closely associated with the occurrence of ischemic events.Intraplaque neovascularization(IPN),as a characteristic component of vulnerable plaques,participates in the formation of carotid atherosclerotic plaques through a variety of mechanisms.This review focuses on the relationship between IPN grading and the degrees of carotid atherosclerosis.

关 键 词：动脉粥样硬化 缺血性事件 斑块内新生血管 颈动脉狭窄 

分 类 号：R743[医药卫生—神经病学与精神病学]