鸦胆子油乳联合化疗治疗晚期非小细胞肺癌的临床效果分析  

Clinical Effect Analysis of Fructus Bruccae Emulsion Combined with Che⁃motherapy in the Treatment of Advanced Non-small Cell Lung Carcinoma

作　　者：王丽丽[1] 尹敏[1] 郭依龙[1] WANG Lii;YIN Min;GUO Yiong(Department of Radiotherapy,Pizhou People's Hospital,Pizhou,Jiangsu Province,221300 China)

机构地区：[1]邳州市人民医院放疗科,江苏邳州221300

出　　处：《系统医学》2023年第22期172-174,182,共4页Systems Medicine

基　　金：徐州医科大学附属医院发展基金-附属邳州医院专项资助项目(ZX202202)。

摘　　要：目的 分析鸦胆子油乳联合化疗治疗晚期非小细胞肺癌(non-small cell lung carcinoma, NSCLC)的临床价值。方法 选择2020年2月—2023年2月在邳州市人民医院接受治疗的76例晚期NSCLC患者为研究对象,以随机数表法分为对照组和观察组,各38例。对照组采用单纯化疗,观察组采用鸦胆子油乳联合化疗。比较两组治疗效果、生存质量及不良反应。结果 两组治疗效果对比,差异无统计学意义(Z=1.169,P>0.05)。治疗后,观察组卡氏评分为(85.56±7.23)分,较对照组的(78.26±6.41)分更高,差异有统计学意义(t=4.657,P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论 鸦胆子油乳联合化疗治疗NSCLC对总体疗效影响不大,但可提升患者生存质量,且不会增加药物不良反应。Objective To analyze the clinical value of fructus bruccae emulsion combined with chemotherapy in the treatment of advanced non-small cell lung carcinoma(NSCLC).Methods A total of 76 patients with advanced NSCLC who received treatment in Pizhou People's Hospital from February 2020 to February 2023 were selected as the study subjects.They were divided into control group and observation group by random number table method,with 38 cases in each group.The control group was treated with chemotherapy alone,and the observation group was treated with bru-cea oil emulsion combined with chemotherapy.The treatment effect,quality of life and adverse reactions were com-pared between the two groups.Results There was no statistically significant difference in treatment effect between the two groups(Z=1.169,P>0.05).After treatment,the Kaffir score of the observation group was(85.56±7.23)points,which was higher than that of the control group(78.26±6.41)points,and the difference was statistically significant(t=4.657,P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Fructus bruccae emulsion combined with chemotherapy in the treatment of NSCLC has little effect on the overall efficacy,but can improve the quality of life of patients without increasing adverse drug reac-tions.

关 键 词：鸦胆子油乳 非小细胞肺癌 化疗 不良反应 

分 类 号：R734[医药卫生—肿瘤]