超声电导仪导入中药穴位贴联合常规止痛药物在晚期消化道肿瘤癌痛患者中的应用效果  

Sonophoresis Transdemal Equipment guided Acupoint Herbal Plaster combined with Pain Relief Drug for Cancer Pain in Patients with Advanced Digestive Tract Tumors

作　　者：吴雅媛 张静[1] 张丰国 Wu Yayuan;Zhang Jing;Zhang Feng-Guo(The First Affiliated Hospital of Xingtai Medical College,Xingtai 054001,Hebei Province,China)

机构地区：[1]邢台医学高等专科学校第一附属医院,河北邢台054001

出　　处：《中外医药研究》2023年第27期102-104,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：2021年邢台市重点研发计划自筹项目(编号:2021ZC193)。

摘　　要：目的:探讨超声电导仪导入中药穴位贴联合常规止痛药物在晚期消化道肿瘤癌痛患者中的应用效果。方法:选取2021年8月—2022年4月邢台医学高等专科学校第一附属医院收治的晚期消化道肿瘤癌痛患者90例作为研究对象,随机分为两组,各45例。对照组应用阿片类药物治疗,试验组在对照组基础上应用超声电导仪导入中药穴位贴治疗。比较两组治疗效果。结果:治疗前,两组疼痛评分比较,差异无统计学意义(P>0.05);治疗后,两组疼痛评分均低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.001)。试验组治疗总有效率高于对照组,差异有统计学意义(P=0.036)。治疗前,两组日平均爆发痛发作次数比较,差异无统计学意义(P>0.05);治疗后,两组日平均爆发痛发作次数均少于治疗前,且试验组少于对照组,差异有统计学意义(P<0.001)。治疗前,两组5-羟色胺(5-HT)水平比较,差异无统计学意义(P>0.05);治疗后,两组5-HT水平均低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.001)。治疗前,两组汉密尔顿抑郁量表(HAMD)评分比较,差异无统计学意义(P>0.05);治疗后,两组HAMD评分均低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.001)。结论:超声电导仪导入中药穴位贴联合常规止痛药物在晚期消化道肿瘤癌痛患者中的应用效果,可减轻患者疼痛程度,减少爆发痛发作次数,降低5-HT水平,改善抑郁情绪。Objective:To explore the application effect of sonophoresis transdemal equipment guided acupoint herbal plaster combined with pain relief drug for cancer pain in patients with advanced digestive tract tumors.Methods:90 patients with advanced gastrointestinal tumor cancer pain admitted to the First Affiliated Hospital of Xingtai Medical College of Higher Education from August 2021 to April 2022 were selected as the study subjects,and were randomly divided into two groups of 45 cases each.The control group was treated with opioids,and the experimental group was treated with sonophoresis transdemal herbal delivery on acupoints on the basis of the control group.the therapeutic effects of the two groups were compared.Results:Before treatment,the pain scores of the two groups were not statistically significant(P>0.05);after treatment,the pain scores of the two groups were lower than those before treatment,and the experimental group was lower than that of the control group,and the difference was statistically significant(P<0.001).The total effective rate of treatment in the experimental group was higher than that in the control group,and the difference was statistically significant(P=0.036).Before treatment,the average daily number of eruptive pain episodes in the two groups was not statistically significant(P>0.05);after treatment,the frequency of eruptive pain episodes in the two groups was less than that before treatment,and the experimental group was less than that of the control group,with a statistically significant difference(P<0.001).Before treatment,5-hydroxytryptamine(5-HT)levels in the two groups were compared,and the difference was not statistically significant(P>0.05);after treatment,5-HT levels in the two groups were lower than before treatment,and the experimental group was lower than the control group,and the difference was statistically significant(P<0.001).Before treatment,the Hamilton Depression Scale(HAMD)scores of the two groups were compared,and the difference was not statistically significant(P>0.

关 键 词：中药超声导入 中药穴位贴 消化道肿瘤 癌痛 

分 类 号：R73[医药卫生—肿瘤]