根管治疗中Vitapex糊剂与奥硝唑碘仿糊剂对窦道型根尖周炎的疗效比较  

Comparison of curative effect of Vitapex paste and Ornidazole iodoform paste on sinus type periapical inflammation in root canal treatment

作　　者：侯佳丽[1] 蔡佳[1] 江煜[1] Hou Jia-li;Cai Jia;Jiang Yu(Department of Stomatology,Haici Hospital(Qingdao Hospital of Traditional Chinese Medicine),Qingdao University,Qingdao,Shandong 266000,China)

机构地区：[1]青岛大学附属青岛市海慈医院(青岛市中医医院)口腔科,山东青岛266000

出　　处：《中国现代医学杂志》2024年第1期89-93,共5页China Journal of Modern Medicine

基　　金：山东省自然科学基金面上项目(No:ZR202103030420)。

摘　　要：目的分析根管治疗中Vitapex糊剂与奥硝唑碘仿糊剂对窦道型根尖周炎疗效的影响。方法选取2019年1月—2022年2月青岛大学附属青岛市海慈医院收治的118例窦道型根尖周炎患者,以随机数字表法分为研究组和对照组,各59例。两组均进行根管治疗,对照组充填奥硝唑碘仿糊剂,研究组充填Vitapex糊剂,治疗后随访6个月。比较两组充填治疗后的疼痛反应、窦道愈合情况、根尖愈合情况、综合疗效及牙周炎症因子(高敏C反应蛋白、白细胞介素-6、白细胞介素-8)水平。结果两组充填治疗后疼痛反应发生率比较,差异无统计学意义(P>0.05)。研究组窦道愈合率高于对照组(P<0.05)。两组治疗前、治疗3个月、治疗6个月的根尖透射区面积比较,采用重复测量设计的方差分析,结果:(1)不同时间点的根尖透射区面积有差异(P<0.05);(2)两组的根尖透射区面积有差别(P<0.05),研究组治疗3个月、治疗6个月的根尖透射区面积均低于对照组;(3)两组根尖透射区面积的变化趋势有差异(P<0.05)。研究组的成功率高于对照组(P<0.05)。研究组治疗前后的高敏C反应蛋白、白细胞介素-6、白细胞介素-8差值均高于对照组(P<0.05)。结论与奥硝唑碘仿糊剂比较,Vitapex糊剂对窦道型根尖周炎患者根管治疗的窦道愈合、根尖愈合及减轻牙周炎症反应方面更具优势,综合治疗效果更佳。Objective To analyze the impact of Vitapex paste and metronidazole iodine paste on the efficacy of root canal treatment in patients with sinus tract-type apical periodontitis.Methods A total of 118 patients diagnosed with sinus tract-type apical periodontitis at Qingdao Hai Ci Hospital affiliated with Qingdao University from January 2019 to February 2022 were selected.Using a random number table,the patients were divided into a study group and a control group,with 59 patients in each group.Both groups underwent root canal treatment,with the control group filled with metronidazole iodine paste and the study group filled with Vitapex paste.Follow-up was conducted for 6 months after treatment.The post-filling pain reaction,sinus tract healing,apical healing,comprehensive efficacy,and levels of periodontal inflammatory factors(high-sensitivity C-reactive protein,interleukin-6,interleukin-8)were compared between the two groups.Results The incidence of post-filling pain reactions was comparable between the two groups(P>0.05).The study group showed a higher sinus tract healing rate than the control group(P<0.05).The root apex transparency area at different time points showed differences(P<0.05)and the study group had a lower root apex transparency area at 3 and 6 months compared to the control group(P<0.05).The change trend in the root apex transparency area differed between the two groups(P<0.05).The success rate in the study group was higher than in the control group(P<0.05).The changes in high-sensitivity C-reactive protein,interleukin-6,and interleukin-8 values before and after treatment were higher in the study group than in the control group(P<0.05).Conclusion Compared to metronidazole iodine paste,Vitapex paste demonstrated superior advantages in sinus tract healing,apical healing,and reduction of periodontal inflammatory responses in patients with sinus tract-type apical periodontitis undergoing root canal treatment.The overall treatment effect was better with Vitapex paste.

关 键 词：窦道型根尖周炎 根管治疗 VITAPEX糊剂 奥硝唑碘仿糊剂 效果 

分 类 号：R781.3[医药卫生—口腔医学]