OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity  

作　　者：Hong-Xia Gong Bin Wu Shi-Yong Xie Wei Zhang Song Chen 

机构地区：[1]Tianjin Key Lab of Ophthalmology and Visual Science,Department of Ophthalmology for Integrated Traditional Chinese and Western Medicine,Tianjin Eye Hospital,Tianjin 300020,China [2]Clinical College of Ophthalmology,Tianjin Medical University,Tianjin 300010,China [3]Eye Hospital Affiliated to Nankai University,Tianjin 300020,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第2期289-296,共8页国际眼科杂志（英文版）

基　　金：Supported by Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-016A).

摘　　要：AIM:To observe the retinal and choroidal circulations in patients with non-arteritic permanent central retinal artery occlusion(NA-CRAO)via optical coherence tomography angiography(OCTA)and analyze their correlation with visual acuity.METHODS:Sixty-two eyes with clinically confirmed acute NA-CRAO were included in the study and divided into:A type(mild n=29),B type(moderate n=27)and C type(severe n=6)based on the degree of visual loss,retinal edema,and arterial blood flow delay in fundus fluorescence angiography(FFA).Contralateral healthy eyes were used as the control group.Best-corrected visual acuity(BCVA),slit lamp microscopy,indirect ophthalmoscopy,fundus color photography,OCTA,and FFA were performed.Spearman’s correlation analysis was used to determine the correlations between retinal and choroidal vessels and visual acuity.RESULTS:There were no statistically significant differences in age,gender,and intraocular pressure among the three types and the control group(P>0.05).Vessel density in deep capillary plexus(VD-DCP)significantly decreased(P<0.05)in all three types of NA-CRAO patients compared to the control group.Vessel density in superficial vascular plexus(VD-SVP)significantly decreased(P<0.05)in type A patients and choriocapillaris flow area significantly decreased(P<0.05)in type B and type C patients compared to the control group;while outer retinal flow areas significantly increased in the type A(P<0.05)and decreased in type C patients(P<0.05).The retinal thickness significantly increased in type C group(P<0.05).The VD-SVP at fovea in the type A was significantly lower than both of type B and C.The VD-SVP at nasal parafovea in type A and B was significantly lower than type C(P<0.05).The logMAR BCVA of type A was significantly better than that of type B and C groups(P<0.05).Spearman’s correlation analysis showed that the logMAR BCVA was positively correlated with VD-SVP at fovea(r=0.679,P=0.031)and nasal parafovea(r=0.826,P=0.013).CONCLUSION:OCTA is valuable for assessing retinal ischemia,and evalu

关 键 词：non-arteritic central retinal artery occlusion fundus fluorescence angiography optical coherence tomography angiography retinal vessel density visual acuity 

分 类 号：R774.1[医药卫生—眼科]