功能MRI探索2型糖尿病神经血管耦联改变机制进展  

Progresses of functional MRI for exploring mechanism of neurovascular coupling changes in diabetes mellitus type 2

作　　者：杨东 许珊 汪旭洋 都丽娜 林琳[1] 沈晶[1] 伍建林[1] YANG Dong;XU Shan;WANG Xuyang;DU Lina;LIN Lin;SHEN Jing;WU Jianlin(Department of Radiology,Affiliated Zhongshan Hospital of Dalian University,Dalian 116000,China)

机构地区：[1]大连大学附属中山医院放射科,辽宁大连116000

出　　处：《中国医学影像技术》2024年第1期125-129,共5页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(82071911);大连市科技创新基金(2021JJ12SN38)。

摘　　要：2型糖尿病(T2DM)认知功能损伤与神经血管耦联(NVC)改变存在密切关系,但目前对于具体机制尚不完全清楚。利用功能MRI(fMRI)技术可联合解析T2DM患者NVC改变,为揭示T2DM所致认知功能障碍的机制提供了新思路。本文就fMRI探索T2DM所致NVC改变进展进行综述。The cognitive impairment of diabetes mellitus type 2(T2DM)is closely related to neurovascular coupling(NVC)changes,but the exact mechanism remains unclear.Functional MRI(fMRI)technology were able to jointly analyze NVC changes of T2DM,providing new ideas for revealing the mechanism of cognitive dysfunction caused by T2DM.The progresses of fMRI for exploring NVC changes in T2DM were reviewed in this article.

关 键 词：糖尿病 2型 神经血管耦联 脑血管循环 磁共振成像 

分 类 号：R741.02[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]