帕金森病伴便秘患者肛管直肠测压研究与应用现状  

Research and application of anorectal manometry in Parkinson’s disease with constipation

作　　者：李海悦 董钊瑜 李朝 费楠 陆艳[2] LI Haiyue;DONG Zhaoyu;LI Zhao(Graduate School of Nanjing University of Chinese Medicine,Nanjing 210003,China)

机构地区：[1]南京中医药大学研究生院,210003 [2]南京中医药大学附属南京中医院脑病科

出　　处：《临床神经病学杂志》2023年第6期470-473,共4页Journal of Clinical Neurology

基　　金：国家自然科学基金青年基金资助项目(81804022);全国中医药创新骨干人才培养项目(国中医药人教函[2019]128号);第二批江苏省名老中医药专家传承工作室建设项目(苏中医科教[2016]6号)。

摘　　要：帕金森病(PD)是一种中老年神经系统变性疾病,便秘是PD最典型的非运动症状之一。肛管直肠测压能够客观地反映肛管直肠的运动和感觉功能,是检查肛门直肠功能、判断便秘类型、评估便秘治疗效果必备的检测之一。本文阐述了肛管直肠测压的检测指标及意义,总结PD伴便秘患者肛管直肠测压的特点为肛管最大收缩压下降、直肠推进力不足、直肠敏感度降低,且PD患者的便秘类型以排便时肛管矛盾性收缩或松弛不足的出口梗阻型为主。Parkinson's disease(PD)is the most common neurodegenerative disease in middle-aged and elderly people.Constipation is one of the most common non-motor symptoms of PD.Anorectal manometry can objectively reflect anorectal movement and sensory function,and is one of the necessary tests to check anorectal function,judge the type of constipation,and evaluate the effect of constipation treatment.This paper expounds the detection indicators and significance of anorectal manometry,and summarizes the characteristics of anorectal manometry in PD patients with constipation:decreased maximum anal systolic pressure,insufficient rectal propulsion,decreased rectal sensitivity,and the type of constipation in PD patients is mainly outlet obstruction with contradictory anal contraction or insufficient relaxation during defecation.

关 键 词：帕金森病 便秘 肛管直肠测压 应用 

分 类 号：R742.5[医药卫生—神经病学与精神病学]