MRI对高、低危型胸腺瘤术前鉴别诊断的应用  

The application of MRI in preoperative differentiation of high-and low-risk thymoma

作　　者：古丽米拉·巴巴什 杜晨阳 武方明[1] 蒋日烽[2] Gulimila·Babashi;DU Chenyang;WU Fangming;JIANG Rifeng(Department of Imaging,Xinjiang Changji Hui Autonomous Prefecture People’s Hospital,Changji 831100,China;Department of Radiology,Fujian Medical University Union Hospital,Fuzhou 350001,China)

机构地区：[1]新疆昌吉回族自治州人民医院影像科,新疆昌吉831100 [2]福建医科大学附属协和医院放射科,福建福州350001

出　　处：《实用放射学杂志》2023年第12期1945-1948,1956,共5页Journal of Practical Radiology

基　　金：新疆昌吉回族自治州科研基金项目(2021S02-09)。

摘　　要：目的探讨MRI在高、低危型胸腺瘤鉴别诊断中的应用。方法双向性收集经病理证实的胸腺瘤患者资料,根据病理分型对比分析高、低危型胸腺瘤患者间临床资料,病灶MRI图像特征、信号特征及表观扩散系数(ADC)值的差异,最后采用受试者工作特征(ROC)曲线分析筛选出有意义特征,评价其诊断效能及指标联合预测概率。结果临床资料分析差异无统计学意义(P>0.001)。高危型病灶形态多以不规则形为主,低危型病灶形态以规则形为主;高危型病灶边缘多不光整,低危型边缘多光整;高危型病灶强化程度高于低危型、ADC值低于低危型。以上差异均有统计学意义(P<0.001),其中ADC值的曲线下面积(AUC)高于其他指标(AUC=0.968),指标联合预测概率最高(AUC=0.981)。结论MRI对高、低危型胸腺瘤术前鉴别诊断具有很大应用价值。Objective To explore the application of MRI in the differential diagnosis of high-and low-risk thymoma.Methods The data of patients with pathologically confirmed thymoma were collected bidirectionally,and the differences in clinical data,MRI image characteristics of lesions,signal characteristics and apparent diffusion coefficient(ADC)values were compared and analyzed between high-and low-risk thymoma according to the pathological subtype.The receiver operating characteristic(ROC)curve analysis was used to screen out meaningful features,then the diagnostic efficacy and combined prediction probability of indicators were evaluated.Results There was no significant difference in clinical data(P>0.001).The morphology of high-risk lesions was mainly irregular,while that of low-risk lesions was mainly regular.The edges of high-risk lesions were mostly not smooth,and the edges of low-risk lesions were mostly smooth.The enhancement degree of high-risk lesions was higher than that of low-risk lesions,and the ADC value was lower than that of low-risk lesions,with statistical significance(P<0.001),in which the ADC value area under the curve(AUC)was higher than other indicators(AUC=0.968),and the combined prediction probability of indicators was the highest(AUC=0.981).Conclusion MRI shows great potential application value in preoperative differential diagnosis of high-and low-risk thymoma.

关 键 词：高危型胸腺瘤 低危型胸腺瘤 磁共振成像 临床症状 

分 类 号：R736.3[医药卫生—肿瘤] R445.2[医药卫生—临床医学]