非小细胞肺癌采用靶向治疗配合中医药辨证辨病相结合治疗的效果分析  

The Effect of Targeted Therapy Combined with Traditional Chinese Medicine Syndrome Differentiation in the Treatment of Non-Small Cell Lung Cancer

作　　者：黄长明 管伟 HUANG Changming;GUAN Wei(Department of Respiratory and Critical Care,Huai'an Fifth People's Hospital,Huai'an,Jiangsu Province,223300 China)

机构地区：[1]淮安市第五人民医院呼吸与危重症医学科,江苏淮安223300

出　　处：《世界复合医学》2023年第11期33-36,共4页World Journal of Complex Medicine

摘　　要：目的分析靶向治疗配合中医药辨证辨病治疗对非小细胞肺癌的影响。方法随机选取2022年2月—2023年7月于淮安市第五人民医院就诊的80例非小细胞肺癌患者作为研究对象,用掷骰子法分为靶向组和结合组,各40例。靶向组行靶向治疗,结合组在靶向组治疗基础上增加中医药辨证辨病治疗,比较两组患者的治疗总有效率,检测肿瘤标志物及免疫指标,并记录不良反应发生情况。结果治疗后,结合组的治疗总有效率高于靶向组,差异有统计学意义(P<0.05)。治疗后,结合组糖类抗原125和癌胚抗原均低于靶向组,差异有统计学意义(P<0.05)。治疗后,结合组3项免疫指标高于靶向组,差异有统计学意义(P<0.05)。结合组不良反应发生率为5.00%,低于靶向组的12.50%,差异无统计学意义(χ^(2)=1.409,P>0.05)。结论靶向治疗配合中医药辨证辨病治疗可提升治疗总有效率,其不良反应少,能降低肿瘤标志物水平,提升免疫机制,控制非小细胞肺癌的发展。Objective To analyze the impact of targeted therapy combined with traditional Chinese medicine syndrome differentiation treatment on non-small cell lung cancer.Methods 80 non-small cell lung cancer patients who visited the Fifth People's Hospital of Huai'an City from February 2022 to July 2023 were randomly selected as the research subjects.They were divided into a targeted group and a combination group using the dice method,with 40 cases in each group.Targeted treatment was performed in the targeted group,while in the combination group,traditional Chinese medicine syndrome differentiation treatment was added on the basis of targeted treatment.The total effective rate of treatment was compared between the two groups of patients,tumor markers and immune indicators were detected,and the occurrence of adverse reactions was recorded.Results After treatment,the total effective rate of the combination group was higher than that of the targeted group,and the difference was statistically significant(P<0.05).The carbohydrate antigen 125 and carcinoembryonic antigen in the combination group were lower than those in the targeted group after treatment,and the differences were statistically significant(P<0.05).After treatment,the three immune indicators in the combination group were higher than those in the targeted group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the combination group was 5.00%,which was lower than the target group's 12.50%,and the difference was not statistically significant(χ^(2)=1.409,P>0.05).Conclusion Targeted therapy combined with traditional Chinese medicine syndrome differentiation treatment can improve the overall effective rate of treatment,reduce adverse reactions,lower tumor marker levels,enhance immune mechanisms,and control the development of non-small cell lung cancer.

关 键 词：靶向治疗 不良反应 中医药辨证辨病 缓解率 非小细胞肺癌 

分 类 号：R734.2[医药卫生—肿瘤]