外泌体在牙周再生应用的研究进展  

Research progress on the application of exosomes in periodontal regeneration

作　　者：黄欣悦 龚旭[2] 郭维维 张滋彬 公梓昊(综述) 王忠山(审校) HUANG Xinyue;GONG Xu;GUO Weiwei;ZHANG Zibin;GONG Zihao;WANG Zhongshan(State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Stomatology,Department of Prosthodontics,The Third Hospital Affiliated of Air Force Military Medical University,Xi'an 710032;State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Stomatology,Department of Dental Materials,The Third Hospital Affiliated of Air Force Military Medical University,Xi'an 710032;State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Stomatology,Department of Oral and Maxillofacial Surgery,The Third Hospital Affiliated of Air Force Military Medical University,Xi'an 710032;First Battalion,First Cadet Regiment,School of Basic Medicine,Air Force Military Medical University)

机构地区：[1]口颌系统重建与再生全国重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔医学重点实验室,第四军医大学口腔医院修复科,西安710032 [2]口颌系统重建与再生全国重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔医学重点实验室,第四军医大学口腔材料学教研室,西安710032 [3]口颌系统重建与再生全国重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔医学重点实验室,第四军医大学口腔颌面外科,西安710032 [4]空军军医大学基础医学院一大队一队

出　　处：《实用口腔医学杂志》2024年第1期117-121,共5页Journal of Practical Stomatology

基　　金：国家自然科学基金青年项目(编号:81700930);空军军医大学第三附属医院教学研究课题一般项目(编号:2020-34)。

摘　　要：牙周病在中国人群中的患病率高达90%以上,现有治疗技术仅能控制疾病发展,诱导骨组织再生能力成为治疗的希望和难点。外泌体是一类来源于核内体的多囊泡结构物,近年来将其应用于牙周再生领域的研究越来越多。该文将近年来外泌体在牙周再生领域的应用进行综述,有望为牙周再生治疗提供新的思路。The prevalence of periodontal disease in Chinese population is more than 90%.The present treatment techniques can only control the development of the disease,inducement of bone tissue regeneration is a promising strategy and a challenge for the treatment.Exosomes are multivesicle structures derived from endosomes.More and more studies have been conducted on their application in periodontal regeneration.This paper reviews the application of exosome in periodontal regeneration in recent years,which is expected to provide new idea for periodontal regeneration therapy.

关 键 词：外泌体 牙周再生 组织工程 

分 类 号：R781.4[医药卫生—口腔医学]