神经元核内包涵体病视频脑电图随访1例  

Video-electroencephalogram follow-up in internal nuclear inclusion disease:a case report

作　　者：邱建敏 林佳君 游学炼 陈丽芳 林媛 谢凌辉 QIU Jianmin;LIN Jiajun;YOU Xuelian;CHEN Lifang;LIN Yuan;XIE Linhui(The School of Clinical Medicine,Fujian Medical University,Fuzhou 350001,China)

机构地区：[1]福建医科大学临床医学部,福州350001 [2]福建省莆田市第一医院神经内科 [3]福建省莆田市第一医院影像科

出　　处：《中国神经精神疾病杂志》2023年第11期669-674,共6页Chinese Journal of Nervous and Mental Diseases

基　　金：福建省莆田市科技计划项目(编号:2020SY001)。

摘　　要：对1例成年女性神经元核内包涵体病(neuronal nuclear inclusion disease,NIID)患者进行近4年的随访观察,尤其对其视频脑电图(video-electroencephalogram,VEEG)的演变、VEEG的辅助诊断、VEEG对临床转归的预判价值进行总结。我们发现NIID患者的背景节律随疾病的进展出现演变;脑电反应性可预测NIID昏迷的转归;VEEG有助于判断NIID引起的意识障碍是否为非惊厥性癫痫持续状态(nonconvultive status epilepticus,NCSE)。本病例为探索VEEG在NIID中的应用提供了新的思路。An adult female patient of internal nuclear inclusion disease(NIID)with a major clinical manifestation of decreased intelligence and recurrent disturbance of consciousness was followed up for nearly 4 years.In particular,the evolution of the video-electroencephalogram(VEEG),the auxiliary diagnosis of VEEG,and the prediction value of VEEG for clinical outcome were summarized.We found that(1)the background rhythm in NIID patients evolved with the progression of the disease;(2)electroencephalogram reactivity could predict the outcome of NIID coma;(3)VEEG helped to determine whether the consciousness disturbance caused by NIID was due to non-convulsive status epilepticus,This case provides a new idea to explore the application of VEEG in NIID.

关 键 词：神经元核内包涵体病 昏迷 视频脑电图 三相波 脑电反应性 非惊厥性癫痫持续状态 随访 

分 类 号：R742[医药卫生—神经病学与精神病学]