气道支架对中心气道肿瘤患者临床疗效  

Clinical efficacy of airway stents in patients with central airway tumors

作　　者：张婷婷 朱涛峰 陈如华 赵欣 ZHANG Tingting;ZHU Taofeng;CHEN Ruhua;ZHAO Xin(Department of Respiratory and Critical Care Medicine,Yixing Hospital Affiliated to Jiangsu University,Jiangsu Province,Yixing 214200,China;Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Nanjing Medical University,Jiangsu Province,Nanjing 210000,China)

机构地区：[1]江苏大学附属宜兴医院呼吸与危重症医学科,江苏宜兴214200 [2]南京医科大学第一附属医院呼吸与危重症医学科,江苏南京210000

出　　处：《中国医药导报》2023年第35期124-127,共4页China Medical Herald

摘　　要：目的探讨气道支架在中心气道肿瘤治疗中的效果。方法选取2020年1月至2023年3月在南京医科大学第一附属医院及江苏大学附属宜兴医院治疗的中心气道肿瘤患者共80例,给予硬气道支架治疗。观察治疗前后血气分析、肺功能指标、生存质量变化。结果治疗后,动脉血氧分压和动脉血氧饱和度高于治疗前,动脉血二氧化碳分压低于治疗前(P<0.05)。治疗后,第一秒用力呼气量、用力肺活量、最大呼气流量、每分钟最大通气量、肺总量和功能残气量高于治疗前(P<0.05)。治疗后,欧洲癌症研究治疗组织生存质量量表评分总体症状评分低于治疗前,躯体、角色、情绪、认知和社会维度评分高于治疗前(P<0.05)。结论气道支架治疗中心气道肿瘤有较好的效果,明显改善患者血气、肺功能、生存质量指标。Objective To investigate the effect of airway stents in the treatment of central airway tumors.Methods A total of 80 patients with central airway tumors who were treated in the First Affiliated Hospital of Nanjing Medical University and Yixing Hospital Affiliated to Jiangsu University from January 2020 to March 2023 were selected,the airway stents was given.Blood gas analysis,lung function index,and quality of life were observed before and after treatment.Results After treatment,the partial pressure of arterial oxygen and saturation of arterial oxygen were higher than those before treatment,and the fraction of arterial carbon dioxide was lower than that before treatment(P<0.05).After treatment,forced expiratory capacity in first second,forced vital capacity,maximum expiratory flow,maximum gas volume per minute,total lung,and functional residual capacity were higher than those before treatment(P<0.05).After treatment,the overall symptom score of the European Organization Research and treatment quality of life scale was lower than that before treatment,and the physical,role,emotional,cognitive,and social dimension scores were higher than those before treatment(P<0.05).Conclusion Airway stents in the treatment of central airway tumors has a good effect,significantly improving the patient’s blood gas,lung function,and quality of life indicators.The treatment effect may be influenced by age,pathological stage,and stenosis degree.

关 键 词：气道支架 中心气道肿瘤 肺功能 生存质量 治疗效果 

分 类 号：R734.2[医药卫生—肿瘤]